Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.93 |
| ▸ | ALDH3A1 | P30838 | 8/20 | 0.93 |
| ▸ | CES1 | P23141 | 5/20 | 0.93 |
| ▸ | ALDH2 | P05091 | 5/20 | 0.93 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.93 |
| ▸ | ACHE | P22303 | 2/20 | 0.76 |
| ▸ | BCHE | P06276 | 3/20 | 0.73 |
| ▸ | CES2 | O00748 | 1/20 | 0.73 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.71 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.71 |
| ▸ | CASP3 | P42574 | 1/20 | 0.67 |
| ▸ | APAF1 | O14727 | 1/20 | 0.66 |
| ▸ | TP53 | P04637 | 1/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.66 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 1/20 | 0.66 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.66 |
| ▸ | TSHR | P16473 | 1/20 | 0.66 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nitrogen SCHEMBL27935052 | 0.98 | ALDH1A1 (0.90) | ALDH1A1ALDH3A1CES1ALDH2CHRM1 | |
| SCHEMBL2087729 | 0.96 | ALDH1A1 (1.00) | ALDH1A1ALDH3A1CES1ALDH2CHRM1 | |
| SCHEMBL29506660 | 0.96 | ALDH1A1 (1.00) | ALDH1A1ALDH3A1CES1ALDH2CHRM1 | |
| Ammonia Solution, Strong SCHEMBL27858936 | 0.95 | ALDH1A1 (0.96) | ALDH1A1ALDH3A1CES1ALDH2CHRM1 | |
| SCHEMBL18288159 | 0.91 | CES1 (0.90) | ALDH1A1ALDH3A1CES1ALDH2CHRM1 | |
| SCHEMBL28220869 | 0.89 | ALDH1A1 (0.79) | ALDH1A1ALDH3A1CES1ALDH2CHRM1 | |
| SCHEMBL27941794 | 0.87 | ALDH3A1 (0.81) | ALDH1A1ALDH3A1CES1ALDH2CHRM1 | |
| SCHEMBL3027106 | 0.85 | CES1 (1.00) | ALDH1A1ALDH3A1CES1ALDH2CHRM1 | |
| SCHEMBL10960133 | 0.83 | CES1 (0.77) | ALDH1A1ALDH3A1CES1ALDH2CHRM1 | |
| SCHEMBL4597810 | 0.83 | CES1 (0.77) | ALDH1A1ALDH3A1CES1ALDH2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109776384-A | The double quaternary carbon dual oxide benzazolyl compounds of 3- aryl -3 '-amino and its synthetic method and application | 华东师范大学 | 2019-05-21 | — | — | CN | disclosed |