Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC15A1 | P46059 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | CTSL | P07711 | 2/20 | 0.46 |
| ▸ | CTSB | P07858 | 2/20 | 0.46 |
| ▸ | CTSS | P25774 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.44 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.44 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.43 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.43 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7331174 | 0.97 | SLC15A1 (0.52) | SLC15A1ALDH1A1CTSLCTSBCTSS | |
| Hydrochloric Acid SCHEMBL19808961 | 0.97 | SLC15A1 (0.52) | SLC15A1ALDH1A1CTSLCTSBCTSS | |
| Hydrochloric Acid SCHEMBL7331177 | 0.97 | SLC15A1 (0.52) | SLC15A1ALDH1A1CTSLCTSBCTSS | |
| SCHEMBL2779058 | 0.95 | SLC15A1 (0.53) | SLC15A1ALDH1A1CTSLCTSBCTSS | |
| SCHEMBL353327 | 0.95 | SLC15A1 (0.53) | SLC15A1ALDH1A1CTSLCTSBCTSS | |
| SCHEMBL730695 | 0.95 | SLC15A1 (0.53) | SLC15A1ALDH1A1CTSLCTSBCTSS | |
| Phenylalanine SCHEMBL10663101 | 0.88 | SLC7A5 (0.56) | SLC15A1ALDH1A1CTSLCTSBCTSS | |
| Alcohol SCHEMBL28297583 | 0.84 | ALDH1A1 (0.53) | SLC15A1ALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL6711118 | 0.84 | SLC15A1 (0.49) | SLC15A1ALDH1A1CTSLCTSBCTSS | |
| SCHEMBL27552079 | 0.84 | SLC15A1 (0.49) | SLC15A1ALDH1A1CTSLCTSBCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109847455-A | A kind of composite material, preparation method and application for filtering fine particulates | 四川大学 | 2019-06-07 | — | — | CN | disclosed |