SCHEMBL28299149

SCHEMBL28299149

CNc1nc(N)nc(N)n1.C[O]

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.38
CA1 P00915 4/20 0.35
CA2 P00918 4/20 0.35
CA9 Q16790 4/20 0.35
CA12 O43570 2/20 0.35
NUDT1 P36639 3/20 0.34
CA4 P22748 1/20 0.34
CA6 P23280 1/20 0.34
CA5A P35218 1/20 0.34
CA7 P43166 1/20 0.34
CA13 Q8N1Q1 1/20 0.34
CA14 Q9ULX7 1/20 0.34
MAPT P10636 2/20 0.33
HTR6 P50406 2/20 0.33
CYP2C19 P33261 2/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2C9 P11712 1/20 0.33
RAB9A P51151 1/20 0.33
LMNA P02545 1/20 0.33
KDM4E B2RXH2 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9910 0.94 ALDH1A1 (0.40) ALDH1A1CA1CA2CA9CA12
Formaldehyde SCHEMBL7191836 0.92 LMNA (0.37) ALDH1A1CA1CA2CA9CA12
Hydrochloric Acid SCHEMBL11061003 0.92 ALDH1A1 (0.39) ALDH1A1CA1CA2CA9CA12
SCHEMBL11394714 0.92 ALDH1A1 (0.39) ALDH1A1CA1CA2CA9CA12
Ammonia Solution, Strong SCHEMBL28937474 0.92 ALDH1A1 (0.39) ALDH1A1CA1CA2CA9CA12
SCHEMBL25422725 0.92 ALDH1A1 (0.42) ALDH1A1CA1CA2CA9CA12
Water SCHEMBL14861606 0.92 ALDH1A1 (0.39) ALDH1A1CA1CA2CA9CA12
Hydrochloric Acid SCHEMBL11062549 0.89 ALDH1A1 (0.38) ALDH1A1CA1CA2CA9CA12
Methyl Alcohol SCHEMBL28283377 0.89 LMNA (0.39) ALDH1A1CA1CA2CA9CA12
SCHEMBL10896684 0.88 PDE4A (0.39) ALDH1A1CA1CA2CA9CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109862790-A Water soluble controlled release compositions and methods of making and using the same 海怡弥私人有限公司 2019-06-07 CN disclosed