Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 4/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.56 |
| ▸ | GMNN | O75496 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | THPO | P40225 | 1/20 | 0.54 |
| ▸ | MTOR | P42345 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.54 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7296894 | 0.98 | OPRM1 (0.58) | OPRM1KCNH2GMNNTP53CYP3A4 | |
| SCHEMBL5402985 | 0.84 | PRMT3 (0.71) | OPRM1GMNNTP53CYP3A4ALOX15 | |
| SCHEMBL6164511 | 0.84 | GRIN2B (0.54) | OPRM1GMNNTP53CYP3A4ALOX15 | |
| SCHEMBL27495861 | 0.84 | SLC6A2 (0.53) | OPRM1GMNNTP53CYP3A4ALOX15 | |
| SCHEMBL360084 | 0.83 | KCNH2 (0.77) | KCNH2GRIN2BSLC6A2SLC6A4 | |
| SCHEMBL8302415 | 0.83 | OPRM1 (0.51) | OPRM1GMNNTP53CYP3A4ALOX15 | |
| Hydrochloric Acid SCHEMBL10714052 | 0.83 | PRMT3 (0.69) | OPRM1GRIN2BSLC6A2SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL10712825 | 0.83 | PRMT3 (0.69) | OPRM1GRIN2BSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6217711 | 0.81 | PRMT3 (0.59) | GRIN2B | |
| SCHEMBL8814613 | 0.81 | HRH3 (0.66) | GRIN2BSLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109715631-A | 6 inhibitor of TRAF | 德国亥姆霍兹慕尼黑中心健康与环境研究中心（有限公司） | 2019-05-03 | — | — | CN | claimed |