Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 5/20 | 0.61 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 7/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.54 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.54 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11582855 | 0.87 | MAPK1 (0.58) | MAPK1EPAS1MAPTALDH1A1GAA | |
| SCHEMBL28300996 | 0.87 | AKR1B1 (0.56) | MAPK1EPAS1MAPTALDH1A1GAA | |
| SCHEMBL28301176 | 0.85 | MAPK1 (0.62) | MAPK1EPAS1MAPTALDH1A1GAA | |
| SCHEMBL28300949 | 0.83 | MAPK1 (0.61) | MAPK1EPAS1MAPTALDH1A1GAA | |
| SCHEMBL9210909 | 0.83 | MAPK1 (0.61) | MAPK1EPAS1MAPTALDH1A1GAA | |
| SCHEMBL116971 | 0.83 | MAPK1 (0.65) | MAPK1EPAS1MAPTALDH1A1GAA | |
| SCHEMBL4490148 | 0.83 | MAPK1 (0.61) | MAPK1EPAS1MAPTALDH1A1GAA | |
| SCHEMBL8430862 | 0.83 | MAPK1 (0.61) | MAPK1EPAS1MAPTALDH1A1GAA | |
| SCHEMBL9836462 | 0.81 | KCNMA1 (0.63) | MAPK1EPAS1MAPTALDH1A1GAA | |
| SCHEMBL11199548 | 0.81 | EPAS1 (0.61) | MAPK1EPAS1MAPTALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105622580-B | Benzimidazole as prolyl hydroxylase inhibitors | 詹森药业有限公司 | 2019-06-21 | — | — | CN | disclosed |