Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 5/20 | 0.61 |
| ▸ | MAPT | P10636 | 8/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.53 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.53 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.53 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.53 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28301176 | 0.85 | MAPK1 (0.62) | MAPK1MAPTALDH1A1EPAS1GAA | |
| SCHEMBL28300949 | 0.83 | MAPK1 (0.61) | MAPK1MAPTALDH1A1EPAS1GAA | |
| SCHEMBL4490148 | 0.83 | MAPK1 (0.61) | MAPK1MAPTALDH1A1EPAS1GAA | |
| SCHEMBL8430862 | 0.83 | MAPK1 (0.61) | MAPK1MAPTALDH1A1EPAS1GAA | |
| SCHEMBL116971 | 0.83 | MAPK1 (0.65) | MAPK1MAPTALDH1A1EPAS1GAA | |
| SCHEMBL28299521 | 0.83 | MAPK1 (0.61) | MAPK1MAPTALDH1A1EPAS1GAA | |
| SCHEMBL11459145 | 0.81 | KCNMA1 (0.67) | MAPK1MAPTALDH1A1EPAS1GAA | |
| SCHEMBL11392520 | 0.81 | MAPK1 (0.84) | MAPK1MAPTALDH1A1EPAS1GAA | |
| SCHEMBL116538 | 0.81 | MAPK1 (0.62) | MAPK1MAPTALDH1A1EPAS1GAA | |
| SCHEMBL11582855 | 0.81 | MAPK1 (0.58) | MAPK1MAPTALDH1A1EPAS1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0001019-A1 | Phenylhydrazones, their use in insecticidal compositions and methods for their preparation | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 1979-03-07 | — | — | EP | claimed |
| EP-0412849-B1 | Azole pesticides | AGREVO UK LTD (GB) | 1995-12-20 | — | — | EP | disclosed |
| CN-1025582-C | Azole pesticides | SCHERING AGROCHEMICALS LTD (GB) | 1994-08-10 | — | — | CN | disclosed |
| US-5189053-A | Insecticide, acaricide and endoparasiticide | SCHERING AGROCHEMICALS LIMITED (GB) | 1993-02-23 | — | — | US | disclosed |
| EP-0324988-B1 | 4-CHLOR-3-SULFAMOYL BENZOIC ACID HYDRAZIDES, PROCESS FOR THEIR PREPARATION, MEDICINES CONTAINING THEM AND USE OF THESE COMPOUNDS IN THE PREPARATION OF DIURETIC AND SALT REDUCING ACTIVITY MEDICINES | CHINOIN GYOGYSZER ES VEGYESZET (HU) | 1992-04-29 | — | — | EP | disclosed |
| US-5109012-A | 2-IMIDAZOL(IN)E SUBSTITUTED ARYL-1,2,3-TRIAZOLE PESTICIDES | SCHERING AGROCHEMICALS LIMITED (GB) | 1992-04-28 | — | — | US | disclosed |
| CN-1049341-A | AZOLE PESTICIDES | SCHERING AGROCHEMICALS LTD (GB) | 1991-02-20 | — | — | CN | disclosed |
| EP-0412849-A2 | Azole pesticides | AgrEvo UK Limited (GB) | 1991-02-13 | — | — | EP | disclosed |
| US-4916149-A | Diuretic and saluretic 4-chloro-3-sulfamoylbenzoic acid hydrazides | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT. (HU) | 1990-04-10 | — | — | US | disclosed |
| CN-1037336-A | Novel 4-chloro-3-sulphonamide benzoyl hydrazine-preparation method contains the drug component and the medical use thereof of this compound | CHINOIN GYOGYSZER ES VEGYESZET (HU) | 1989-11-22 | — | — | CN | disclosed |
| EP-0324988-A1 | 4-Chlor-3-sulfamoyl benzoic acid hydrazides, process for their preparation, medicines containing them and use of these compounds in the preparation of diuretic and salt reducing activity medicines | CHINOIN Gyogyszer és Vegyészeti Termékek Gyára RT. (HU) | 1989-07-26 | — | — | EP | disclosed |
| EP-0034945-B1 | N-PHENYLPYRAZOLE DERIVATIVES | MAY & BAKER LIMITED (GB) | 1985-08-07 | — | — | EP | disclosed |
| US-4496390-A | WEED-CONTRTOLLING HERBICIDES | MAY & BAKER LIMITED (GB) | 1985-01-29 | — | — | US | disclosed |
| EP-0034945-A2 | N-phenylpyrazole derivatives | MAY & BAKER LIMITED (GB) | 1981-09-02 | — | — | EP | disclosed |