Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 4/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | CASP7 | P55210 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.51 |
| ▸ | PHGDH | O43175 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | IDO1 | P14902 | 1/20 | 0.49 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL397773 | 0.82 | MAPK1 (0.77) | MAPK1L3MBTL1TDP1ALDH1A1CASP7 | |
| SCHEMBL12655445 | 0.79 | ALDH1A1 (0.56) | MAPK1L3MBTL1TDP1ALDH1A1CASP7 | |
| SCHEMBL12205174 | 0.78 | MAPK1 (0.60) | MAPK1L3MBTL1TDP1ALDH1A1CASP7 | |
| SCHEMBL355102 | 0.78 | MAPK1 (0.60) | MAPK1L3MBTL1TDP1ALDH1A1CASP7 | |
| SCHEMBL728448 | 0.78 | MEN1 (0.61) | MAPK1L3MBTL1TDP1ALDH1A1CASP7 | |
| SCHEMBL856759 | 0.78 | MAPK1 (0.60) | MAPK1L3MBTL1TDP1ALDH1A1CASP7 | |
| SCHEMBL950729 | 0.78 | MAPK1 (0.60) | MAPK1L3MBTL1TDP1ALDH1A1CASP7 | |
| SCHEMBL973213 | 0.78 | MAPK1 (0.60) | MAPK1L3MBTL1TDP1ALDH1A1CASP7 | |
| SCHEMBL297021 | 0.78 | MAPK1 (0.60) | MAPK1L3MBTL1TDP1ALDH1A1CASP7 | |
| SCHEMBL373368 | 0.78 | MAPK1 (0.60) | MAPK1L3MBTL1TDP1ALDH1A1CASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105622580-B | Benzimidazole as prolyl hydroxylase inhibitors | 詹森药业有限公司 | 2019-06-21 | — | — | CN | disclosed |