Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | RPA1 | P27694 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | STAT1 | P42224 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CACNB4 | O00305 | 4/20 | 0.37 |
| ▸ | CACNA1A | O00555 | 4/20 | 0.37 |
| ▸ | CACNA1G | O43497 | 4/20 | 0.37 |
| ▸ | CACNG3 | O60359 | 4/20 | 0.37 |
| ▸ | CACNA1F | O60840 | 4/20 | 0.37 |
| ▸ | CACNA1H | O95180 | 4/20 | 0.37 |
| ▸ | CACNB3 | P54284 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28847584 | 0.83 | RPA1 (0.39) | HTR1AHTR7RPA1EGFRNPC1 | |
| SCHEMBL28301248 | 0.81 | GAA (0.49) | NPC1MAPTMAPK1RAB9ASMN1; SMN2 | |
| SCHEMBL28873761 | 0.79 | NPSR1 (0.44) | HTR1AHTR7RPA1EGFRNPC1 | |
| SCHEMBL28847505 | 0.79 | CYP1A2 (0.44) | RPA1NPC1MAPTSTAT1RAB9A | |
| SCHEMBL28953730 | 0.78 | KDM4E (0.38) | RPA1NPC1MAPTMAPK1STAT1 | |
| SCHEMBL28299743 | 0.77 | RAB9A (0.53) | HTR1AHTR7RPA1EGFRNPC1 | |
| SCHEMBL28299729 | 0.76 | NPC1 (0.46) | HTR1AHTR7RPA1EGFRNPC1 | |
| SCHEMBL28847542 | 0.76 | CACNA1B (0.35) | HTR1AHTR7RPA1EGFRNPC1 | |
| SCHEMBL28301021 | 0.74 | CA1 (0.55) | RPA1RAB9AFABP3FABP4 | |
| SCHEMBL28300981 | 0.73 | CCKAR (0.45) | RPA1RAB9ACACNB4CACNA1ACACNA1G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109890822-B | Inhibitors of cellular metabolic processes | 安吉奥斯医药品有限公司 | 2022-08-30 | — | — | CN | disclosed |
| CN-109890822-A | INHIBITORS OF CELLULAR METABOLIC PROCESSES | 安吉奥斯医药品有限公司 | 2019-06-14 | — | — | CN | disclosed |