Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11174975 | 0.84 | MEN1 (0.42) | MEN1KMT2ANPSR1L3MBTL1KDM4E | |
| SCHEMBL27471665 | 0.82 | MEN1 (0.41) | MEN1KMT2ANPSR1L3MBTL1KDM4E | |
| SCHEMBL30185875 | 0.82 | L3MBTL1 (0.47) | MEN1KMT2ANPSR1L3MBTL1HPGD | |
| SCHEMBL4787649 | 0.82 | EPHX1 (0.50) | MEN1KMT2ANPSR1L3MBTL1KDM4E | |
| SCHEMBL1835772 | 0.82 | L3MBTL1 (0.47) | MEN1KMT2ANPSR1L3MBTL1HPGD | |
| SCHEMBL28349710 | 0.81 | MEN1 (0.39) | MEN1KMT2ANPSR1L3MBTL1KDM4E | |
| SCHEMBL11712958 | 0.81 | MEN1 (0.39) | MEN1KMT2ANPSR1L3MBTL1KDM4E | |
| SCHEMBL4193615 | 0.81 | MEN1 (0.39) | MEN1KMT2ANPSR1L3MBTL1KDM4E | |
| SCHEMBL6031816 | 0.81 | PTGS2 (0.52) | KDM4EHPGDTSHRALDH1A1 | |
| SCHEMBL2952279 | 0.81 | IDO1 (0.42) | IDO1NPSR1L3MBTL1HTTFOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114891053-A | Compositions comprising reversibly modified oligonucleotides and uses thereof | 迪克纳制药公司 | 2022-08-12 | — | — | CN | disclosed |
| CN-109890207-B | Compositions comprising reversibly modified oligonucleotides and uses thereof | 迪克纳制药公司 | 2022-05-27 | — | — | CN | disclosed |
| CN-109890207-A | COMPOSITIONS COMPRISING REVERSIBLY MODIFIED OLIGONUCLEOTIDES AND USES THEREOF | 迪克纳制药公司 | 2019-06-14 | — | — | CN | disclosed |