Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.51 |
| ▸ | SRC | P12931 | 1/20 | 0.51 |
| ▸ | ERN1 | O75460 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TLR2 | O60603 | 1/20 | 0.47 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.47 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.46 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL269268 | 0.91 | ALDH1A1 (0.56) | ABCG2SRCERN1ALDH1A1MAPT | |
| SCHEMBL31474876 | 0.91 | ALDH1A1 (0.56) | ABCG2SRCERN1ALDH1A1MAPT | |
| O-Veratraldehyde SCHEMBL8706125 | 0.86 | SRC (0.59) | ABCG2SRCERN1ALDH1A1MAPT | |
| SCHEMBL27620236 | 0.84 | TUBB1 (0.46) | ABCG2SRCERN1ALDH1A1MAPT | |
| SCHEMBL8506220 | 0.84 | ERN1 (0.46) | ABCG2SRCERN1ALDH1A1MAPT | |
| SCHEMBL8636872 | 0.82 | LMNA (0.46) | ABCG2ERN1ALDH1A1MAPTPOLB | |
| SCHEMBL14112796 | 0.81 | CA1 (0.46) | ABCG2SRCERN1ALDH1A1MAPT | |
| SCHEMBL18188991 | 0.81 | ABCG2 (0.50) | ABCG2SRCERN1ALDH1A1MAPT | |
| SCHEMBL29729025 | 0.80 | CA1 (0.59) | ABCG2SRCERN1ALDH1A1MAPT | |
| SCHEMBL3345839 | 0.80 | CA1 (0.59) | ABCG2SRCERN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109734683-B | Method for converting trimetazidine production waste into useful substances | 北京嘉林药业股份有限公司 | 2020-12-18 | — | — | CN | disclosed |
| CN-109734683-A | The method that Trimetazidine production waste is converted to utility | 北京嘉林药业股份有限公司 | 2019-05-10 | — | — | CN | disclosed |