Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | XDH | P47989 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28873605 | 0.90 | XDH (0.52) | NPC1RAB9AALOX15TP53POLB | |
| SCHEMBL28298321 | 0.87 | GRM4 (0.63) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28298330 | 0.86 | RAB9A (0.53) | NPC1RAB9ATP53POLBSMN1; SMN2 | |
| SCHEMBL28298329 | 0.86 | NPC1 (0.51) | NPC1RAB9AALOX15TP53POLB | |
| SCHEMBL28298336 | 0.85 | RAB9A (0.60) | NPC1RAB9ATP53POLBSMN1; SMN2 | |
| SCHEMBL28298340 | 0.84 | RAB9A (0.56) | NPC1RAB9ATP53POLBSMN1; SMN2 | |
| SCHEMBL28299731 | 0.84 | MEN1 (0.61) | POLB | |
| SCHEMBL28298333 | 0.82 | KMT2A (0.53) | NPC1RAB9ATP53SMN1; SMN2XDH | |
| SCHEMBL28299726 | 0.81 | RAB9A (0.57) | NPC1RAB9AALOX15TP53POLB | |
| SCHEMBL28153803 | 0.79 | XDH (0.47) | XDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106674098-B | N- (3- cyano -4- alkoxyl phenyl) pyridine carboxamides and application thereof | 中国医科大学 | 2019-07-02 | — | — | CN | disclosed |