Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 6/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28298369 | 0.97 | GRM4 (0.63) | GRM4KDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28299838 | 0.89 | GRM4 (0.64) | GRM4KDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28298340 | 0.88 | RAB9A (0.56) | NPC1RAB9ASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL28299724 | 0.86 | GRM4 (0.60) | GRM4KDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28298336 | 0.84 | RAB9A (0.60) | NPC1RAB9ASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL28298321 | 0.84 | GRM4 (0.63) | GRM4KDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28298331 | 0.83 | GRM4 (0.61) | GRM4KDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28298334 | 0.83 | GRM4 (0.64) | GRM4KDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28873606 | 0.82 | GRM4 (0.60) | GRM4KDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28298335 | 0.78 | ALDH1A1 (0.53) | ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106674098-B | N- (3- cyano -4- alkoxyl phenyl) pyridine carboxamides and application thereof | 中国医科大学 | 2019-07-02 | — | — | CN | disclosed |