Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.40 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 5/20 | 0.36 |
| ▸ | DRD3 | P35462 | 4/20 | 0.36 |
| ▸ | DRD2 | P14416 | 3/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21945577 | 0.85 | P2RX7 (0.45) | NOTUMBCHELMNAMTORAVPR2 | |
| SCHEMBL2443863 | 0.85 | NOTUM (0.54) | NOTUMBCHELMNAMTORAVPR2 | |
| SCHEMBL2446957 | 0.85 | NOTUM (0.43) | NOTUMBCHELMNAMTORAVPR2 | |
| SCHEMBL2415047 | 0.81 | P2RX7 (0.46) | LMNAP2RX7ADRB1DRD4DRD3 | |
| SCHEMBL20162771 | 0.81 | DRD2 (0.49) | NOTUMMTORP2RX7DRD4DRD3 | |
| SCHEMBL30037628 | 0.81 | DRD2 (0.49) | NOTUMMTORP2RX7DRD4DRD3 | |
| SCHEMBL28619276 | 0.81 | NOTUM (0.40) | NOTUMBCHELMNAMTORAVPR2 | |
| SCHEMBL16810238 | 0.80 | NOTUM (0.47) | NOTUMLMNADRD4DRD3DRD2 | |
| SCHEMBL28622164 | 0.80 | P2RX7 (0.47) | NOTUMBCHELMNAMTORAVPR2 | |
| SCHEMBL27707043 | 0.79 | P2RX7 (0.38) | P2RX7DRD4DRD3DRD2HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109867666-B | Aromatic acetamide compound containing isothiazole ring and application thereof | 沈阳中化农药化工研发有限公司 | 2021-09-07 | — | — | CN | disclosed |
| CN-109867666-A | A kind of fragrant acetamides of the ring containing isothiazole and application thereof | 沈阳中化农药化工研发有限公司 | 2019-06-11 | — | — | CN | disclosed |