Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TOP2A | P11388 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28299745 | 0.85 | CYP2C9 (0.50) | TSHRMEN1KMT2APOLBALOX15 | |
| SCHEMBL28550466 | 0.78 | SLC6A3 (0.53) | TSHRSLC6A3SLC6A4MEN1ALDH1A1 | |
| SCHEMBL22261474 | 0.77 | SLC6A3 (0.54) | TSHRSLC6A3SLC6A4MEN1ALDH1A1 | |
| SCHEMBL13823879 | 0.77 | SLC6A3 (0.55) | TSHRSLC6A3SLC6A4MEN1ALDH1A1 | |
| SCHEMBL28577714 | 0.74 | DNMT1 (0.46) | TSHRMEN1ALDH1A1KMT2ADNMT1 | |
| SCHEMBL12546416 | 0.73 | SLC6A3 (0.47) | TSHRSLC6A3SLC6A4MEN1ALDH1A1 | |
| SCHEMBL22261504 | 0.73 | L3MBTL1 (0.50) | SLC6A3SLC6A4POLBTOP2AMAPT | |
| SCHEMBL1775832 | 0.73 | SLC6A3 (0.74) | TSHRSLC6A3SLC6A4MEN1ALDH1A1 | |
| SCHEMBL27843639 | 0.73 | SLC6A3 (0.74) | TSHRSLC6A3SLC6A4MEN1ALDH1A1 | |
| SCHEMBL29057957 | 0.72 | SLC6A3 (0.55) | TSHRSLC6A3SLC6A4MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109721615-A | Inhibitors of influenza viruses replication and application thereof | 广东东阳光药业有限公司 | 2019-05-07 | — | — | CN | disclosed |