SCHEMBL28299811

SCHEMBL28299811

C#Cc1cc2cc3cc(C#C)c(C#C)cc3cc2cc1C#C

nearest known ligand 0.44

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 1/20 0.31
PTPN6 P29350 1/20 0.31
PTPN11 Q06124 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6889640 0.81 PTPN1 (0.35) PTPN1PTPN6PTPN11
SCHEMBL31638375 0.78 CA1 (0.41)
SCHEMBL21121993 0.78 CA1 (0.41)
SCHEMBL3721462 0.71 ALDH1A1 (0.35)
SCHEMBL12020934 0.67 KDM4E (0.33)
SCHEMBL11126907 0.66 ALDH1A1 (0.40)
SCHEMBL31742506 0.65 USP8 (0.41)
SCHEMBL30957099 0.64 CA1 (0.41)
SCHEMBL9928987 0.64 CYP1B1 (0.40)
SCHEMBL29203830 0.63 CYP1A1 (0.50)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109762085-A A kind of poly- aryne nanometer sheet of Novel compressive and preparation method thereof 中国科学院合肥物质科学研究院 2019-05-17 CN disclosed