SCHEMBL9928987

SCHEMBL9928987

C#Cc1cccc2cc3cccc(C#C)c3cc12

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1B1 Q16678 2/20 0.40
CYP1A1 P04798 1/20 0.40
CYP1A2 P05177 5/20 0.36
ALDH1A1 P00352 4/20 0.36
HSD17B10 Q99714 3/20 0.36
HPGD P15428 2/20 0.36
ERBB2 P04626 1/20 0.34
FYN P06241 1/20 0.34
MAOA P21397 1/20 0.34
ACHE P22303 1/20 0.34
AHR P35869 1/20 0.34
ESR1 P03372 2/20 0.34
ESR2 Q92731 2/20 0.34
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
HTR2A P28223 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
HIF1A Q16665 1/20 0.32
KDM4E B2RXH2 2/20 0.31
GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5438141 0.93 CYP1B1 (0.41) CYP1B1CYP1A1CYP1A2ALDH1A1HSD17B10
SCHEMBL30918302 0.91 ALDH1A1 (0.41) CYP1B1CYP1A1CYP1A2ALDH1A1HSD17B10
SCHEMBL937286 0.91 ALDH1A1 (0.41) CYP1B1CYP1A1CYP1A2ALDH1A1HSD17B10
SCHEMBL28776208 0.90 ALDH1A1 (0.45) CYP1B1CYP1A1CYP1A2ALDH1A1HSD17B10
SCHEMBL11126907 0.89 ALDH1A1 (0.40) CYP1B1CYP1A1CYP1A2ALDH1A1HSD17B10
SCHEMBL5478906 0.89 ALDH1A1 (0.40) CYP1B1CYP1A1CYP1A2ALDH1A1HSD17B10
SCHEMBL6033716 0.88 ALDH1A1 (0.43) CYP1B1CYP1A1CYP1A2ALDH1A1HSD17B10
Biphenyl SCHEMBL22806928 0.84 ALDH1A1 (0.37) CYP1B1CYP1A1CYP1A2ALDH1A1HSD17B10
SCHEMBL28191024 0.84 ALDH1A1 (0.37) CYP1B1CYP1A1CYP1A2ALDH1A1HSD17B10
SCHEMBL689634 0.81 PTPN1 (0.39) CYP1B1CYP1A1ALDH1A1HSD17B10HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140194605-A1 SERS Reporter Molecules and Methods CABOT SECURITY MATERIALS, INC. (US) 2014-07-10 US claimed
US-20120156491-A1 SERS Reporter Molecules and Methods CABOT SECURITY MATERIALS INC. (US) 2012-06-21 US claimed
US-20140194605-A1 SERS Reporter Molecules and Methods CABOT SECURITY MATERIALS, INC. (US) 2014-07-10 US disclosed
US-20120156491-A1 SERS Reporter Molecules and Methods CABOT SECURITY MATERIALS INC. (US) 2012-06-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140194605-A1 SERS Reporter Molecules and Methods SRRT, MYCBP, SPR CYP1B1 2204/4885CYP1A1 839/4885CYP1A2 1660/4885
US-20120156491-A1 SERS Reporter Molecules and Methods SRRT, MYCBP, SPR CYP1B1 2204/4885CYP1A1 839/4885CYP1A2 1660/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.