Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | TAF1 | P21675 | 1/20 | 0.32 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.32 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.32 |
| ▸ | CECR2 | Q9BXF3 | 1/20 | 0.32 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.32 |
| ▸ | TYMP | P19971 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
| ▸ | CES1 | P23141 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4348692 | 0.87 | ADRA1D (0.37) | ADRA1DADRA1AADRA1BBRD4TAF1 | |
| SCHEMBL10981137 | 0.85 | TYMP (0.39) | ADRA1DADRA1AADRA1BTYMP | |
| SCHEMBL7181586 | 0.85 | TYMP (0.39) | ADRA1DADRA1AADRA1BTYMP | |
| SCHEMBL8377767 | 0.83 | ADRA1D (0.31) | ADRA1DADRA1AADRA1B | |
| SCHEMBL9118472 | 0.80 | KDM4E (0.39) | — | |
| SCHEMBL2983409 | 0.80 | ADRA1D (0.34) | ADRA1DADRA1AADRA1BBRD4TAF1 | |
| SCHEMBL10428820 | 0.80 | ADRA1D (0.34) | ADRA1DADRA1AADRA1BBRD4TAF1 | |
| SCHEMBL3235865 | 0.80 | ADRA1D (0.37) | ADRA1DADRA1AADRA1BBRD4TAF1 | |
| SCHEMBL2930015 | 0.80 | HASPIN (0.35) | ADRA1DADRA1AADRA1BBRD4TAF1 | |
| SCHEMBL17371770 | 0.77 | HASPIN (0.43) | ADRA1DADRA1AADRA1BTYMP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101253199-B | Agonists, antagonists and immunotoxins for immunomodulating tumor necrosis factor receptor 25(TNFR25) | 迈阿密大学 | 2019-06-14 | — | — | CN | disclosed |