Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | TYMP | P19971 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | WEE1 | P30291 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | TAF1 | P21675 | 1/20 | 0.32 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26787539 | 0.89 | ALDH1A1 (0.44) | ADRA1DADRA1AADRA1BPDE4APDE4B | |
| SCHEMBL4348692 | 0.87 | ADRA1D (0.37) | ADRA1DADRA1AADRA1BTYMPKMT2A | |
| SCHEMBL338056 | 0.83 | TYMP (0.32) | ADRA1DADRA1AADRA1BTYMP | |
| SCHEMBL10428820 | 0.80 | ADRA1D (0.34) | ADRA1DADRA1AADRA1BTYMPBRD4 | |
| SCHEMBL9118472 | 0.80 | KDM4E (0.39) | PDE4APDE4BPDE4CPDE4DHPGD | |
| SCHEMBL3235865 | 0.80 | ADRA1D (0.37) | ADRA1DADRA1AADRA1BTYMPBRD4 | |
| SCHEMBL2930015 | 0.80 | HASPIN (0.35) | ADRA1DADRA1AADRA1BTYMPKMT2A | |
| SCHEMBL28299867 | 0.80 | ADRA1D (0.34) | ADRA1DADRA1AADRA1BTYMPBRD4 | |
| SCHEMBL4347789 | 0.78 | TYMP (0.31) | ADRA1DADRA1AADRA1BTYMP | |
| SCHEMBL17371770 | 0.77 | HASPIN (0.43) | ADRA1DADRA1AADRA1BTYMPHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1019423-B1 | METHOD FOR PRODUCING A PENTOPYRANOSYL NUCLEOSIDE | NANOGEN RECOGNOMICS GMBH (DE) | 2003-02-26 | — | — | EP | claimed |
| US-7777024-B2 | Process for preparing a pentopyranosyl nucleic acid conjugate | AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO. (DE) | 2010-08-17 | — | — | US | disclosed |
| US-20090221793-A1 | PROCESS FOR PREPARING A PENTOPYRANOSYL NUCLEIC ACID CONJUGATE | SANOFI-AVENTIS S.A. (FR) | 2009-09-03 | — | — | US | disclosed |
| US-7501506-B2 | Pentopyranosyl nucleic acid conjugates | NANOGEN RECOGNOMICS GMBH (DE) | 2009-03-10 | — | — | US | disclosed |
| US-7153955-B2 | Pentopyranosyl nucleic acid arrays, and uses thereof | NANOGEN RECOGNOMICS GMBH (DE) | 2006-12-26 | — | — | US | disclosed |
| US-20060270840-A1 | Pentopyranosyl nucleic acid conjugates | SANOFI-AVENTIS S.A. (FR) | 2006-11-30 | — | — | US | disclosed |
| EP-1034180-B1 | LINKER NUCLEOSIDE, AND PRODUCTION AND USE OF THE SAME | NANOGEN RECOGNOMICS GMBH (DE) | 2006-03-29 | — | — | EP | disclosed |
| US-20050053945-A1 | Process for the preparation of a pentopyranosyl conjugate | NANOGEN RECOGNOMICS GMBH | 2005-03-10 | — | — | US | disclosed |
| US-20050004356-A1 | Linker nucleoside, its preparation and use | NANOGEN RECOGNOMICS GMBH (DE) | 2005-01-06 | — | — | US | disclosed |
| US-20040198966-A1 | Pentopyranosylnucleoside, its preparation and use | NANOGEN RECOGNOMICS GMBH | 2004-10-07 | — | — | US | disclosed |
| EP-1017703-A2 | PENTOPYRANOSYL NUCLEOSIDE, AND PRODUCTION AND USE OF THE SAME | Nanogen Recognomics GmbH (DE) | 2000-07-12 | — | — | EP | disclosed |
| EP-1017704-A2 | USE OF A PENTOPYRANOSYL NUCLEOSIDE CONTAINING CONJUGATE FOR PRODUCING AN ARRAY | Nanogen Recognomics GmbH (DE) | 2000-07-12 | — | — | EP | disclosed |
| WO-1999052923-A2 | METHOD FOR THE PRODUCTION OF PENTOPYRANOSYL NUCLEOSIDES | AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO. KG (DE) | 1999-10-21 | — | — | WO | disclosed |
| WO-1999015540-A2 | METHOD FOR PRODUCING A PENTOPYRANOSYL NUCLEOSIDE | AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO KG (DE) | 1999-04-01 | — | — | WO | disclosed |
| WO-1999015542-A2 | LINKER NUCLEOSIDE, AND PRODUCTION AND USE OF THE SAME | AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO. KG (DE) | 1999-04-01 | — | — | WO | disclosed |
| WO-1999015541-A2 | USE OF A PENTOPYRANOSYL NUCLEOSIDE FOR PRODUCING AN ELECTRONIC COMPONENT, AND CONJUGATES OF SAID PENTOPYRANOSYL NUCLEOSIDE | AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO. KG (DE) | 1999-04-01 | — | — | WO | disclosed |
| WO-1999015539-A2 | PENTOPYRANOSYL NUCLEOSIDE, AND PRODUCTION AND USE OF THE SAME | AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO. KG (DE) | 1999-04-01 | — | — | WO | disclosed |
| EP-0151824-B1 | N-(4-PIPERIDINYL) BICYCLIC CONDENSED 2-IMIDAZOLAMINE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1990-04-04 | — | — | EP | disclosed |
| US-4588722-A | ANTIHISTAMINES, ANTIALLERGENS | JANSSEN PHARMACEUTICA N.V. (BE) | 1986-05-13 | — | — | US | disclosed |
| EP-0151824-A2 | N-(4-piperidinyl) bicyclic condensed 2-imidazolamine derivatives | JANSSEN PHARMACEUTICA N.V. (BE) | 1985-08-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090221793-A1 | PROCESS FOR PREPARING A PENTOPYRANOSYL NUCLEIC ACID CONJUGATE | RNGTT, NT5C3B, FUT6 | ADRA1D 4648/4885ADRA1A 4334/4885ADRA1B 4506/4885 |
| US-20040198966-A1 | Pentopyranosylnucleoside, its preparation and use | FUT6, ST3GAL3, FUT5 | ADRA1D 2351/4885ADRA1A 1787/4885ADRA1B 2368/4885 |
| US-20050004356-A1 | Linker nucleoside, its preparation and use | RNGTT, NSUN2, NSUN3 | ADRA1D 4724/4885ADRA1A 4438/4885ADRA1B 4556/4885 |
| US-20050053945-A1 | Process for the preparation of a pentopyranosyl conjugate | FUT6, FUT5, FUCA2 | ADRA1D 3314/4885ADRA1A 2666/4885ADRA1B 2625/4885 |
| US-20060270840-A1 | Pentopyranosyl nucleic acid conjugates | FUT6, RNGTT, B3GAT3 | ADRA1D 4738/4885ADRA1A 4435/4885ADRA1B 4576/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.