Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLCG1 | P19174 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 5/20 | 0.39 |
| ▸ | NOS3 | P29474 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
| ▸ | FDPS | P14324 | 2/20 | 0.38 |
| ▸ | USP8 | P40818 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL130043 | 0.89 | — | — | |
| SCHEMBL29435709 | 0.89 | — | — | |
| SCHEMBL14484928 | 0.73 | LRRK2 (0.47) | PLCG1NOS3NOS1NOS2USP8 | |
| SCHEMBL2520189 | 0.72 | — | — | |
| SCHEMBL14659250 | 0.72 | TRIM24 (0.52) | PLCG1ELANEMAPTMAPK1KDM4E | |
| Formic Acid SCHEMBL27896714 | 0.72 | LMNA (0.46) | NOS3NOS1NOS2FDPSMAPT | |
| Formic Acid SCHEMBL28014997 | 0.72 | TRIM24 (0.52) | NOS3NOS1NOS2FDPSMAPT | |
| Formic Acid SCHEMBL28079694 | 0.72 | NAPRT (0.46) | NOS3NOS1NOS2FDPSMAPT | |
| SCHEMBL1133218 | 0.71 | USP8 (0.50) | PLCG1NOS3NOS1NOS2USP8 | |
| Formic Acid SCHEMBL30763006 | 0.70 | RAB9A (0.32) | PLCG1ELANEKDM4ENPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107108652-B | BACE1 inhibitors | 豪夫迈·罗氏有限公司 | 2019-06-18 | — | — | CN | disclosed |