Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 2/20 | 0.52 |
| ▸ | MAOB | P27338 | 3/20 | 0.51 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | BACE1 | P56817 | 1/20 | 0.50 |
| ▸ | PTGES | O14684 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6665583 | 0.88 | MAOB (0.55) | MAOBNR4A2MAPTMEN1KMT2A | |
| SCHEMBL5065193 | 0.86 | PARP10 (0.54) | MAOBMAPTMEN1KMT2ALMNA | |
| SCHEMBL4604134 | 0.84 | MEN1 (0.51) | MAOBMAPTMEN1KMT2ALMNA | |
| SCHEMBL6361504 | 0.84 | MEN1 (0.56) | MAOBMAPTMEN1KMT2ALMNA | |
| SCHEMBL10737968 | 0.81 | MEN1 (0.57) | MAOBMAPTMEN1KMT2A | |
| SCHEMBL28499327 | 0.81 | ALDH1A1 (0.62) | MAPTMEN1KMT2ALMNARAB9A | |
| SCHEMBL5119495 | 0.81 | SRD5A2 (0.59) | SRD5A2MAOBNR4A2MAPTMEN1 | |
| SCHEMBL29481015 | 0.81 | MAOB (0.71) | SRD5A2MAOBNR4A2MEN1KMT2A | |
| SCHEMBL26863 | 0.81 | MAOB (0.71) | SRD5A2MAOBNR4A2MEN1KMT2A | |
| SCHEMBL30832846 | 0.81 | MEN1 (0.57) | MAOBMAPTMEN1KMT2ABACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109879832-A | A kind of 4- alkoxy -2- aryl thiol morpholine -3,5- cyclohexadione compounds and preparation method | 武汉工程大学 | 2019-06-14 | — | — | CN | disclosed |