Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.55 |
| ▸ | CTSV | O60911 | 4/20 | 0.54 |
| ▸ | CTSL | P07711 | 4/20 | 0.54 |
| ▸ | BACE1 | P56817 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.51 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.51 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.51 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5065193 | 0.89 | PARP10 (0.54) | MAOBCTSVCTSLBACE1MEN1 | |
| SCHEMBL4936955 | 0.89 | CTSV (0.57) | MAOBCTSVCTSLBACE1MEN1 | |
| SCHEMBL28299950 | 0.88 | SRD5A2 (0.52) | MAOBBACE1MEN1KMT2ANR4A2 | |
| SCHEMBL5875339 | 0.87 | NR4A2 (0.60) | MAOBBACE1NR4A2 | |
| SCHEMBL6361504 | 0.87 | MEN1 (0.56) | MAOBCTSVCTSLBACE1MEN1 | |
| SCHEMBL4604134 | 0.87 | MEN1 (0.51) | MAOBCTSVCTSLBACE1MEN1 | |
| SCHEMBL14392458 | 0.86 | PTGES (0.52) | MAOBCTSVCTSLMEN1KMT2A | |
| SCHEMBL10737968 | 0.85 | MEN1 (0.57) | MAOBMEN1KMT2AMAPT | |
| SCHEMBL30832846 | 0.84 | MEN1 (0.57) | MAOBCTSVCTSLBACE1MEN1 | |
| SCHEMBL1663438 | 0.84 | MEN1 (0.57) | MAOBCTSVCTSLBACE1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1442020-A1 | HETEROCYCLIC DERIVATIVES OF GLYCINAMIDE AND THEIR MEDICAL USE | SmithKline Beecham plc (GB) | 2004-08-04 | — | — | EP | disclosed |
| WO-2003042179-A1 | HETEROCYCLIC DERIVATIVES OF GLYCINAMIDE AND THEIR MEDICAL USE | SMITHKLINE BEECHAM P.L.C. (GB) | 2003-05-22 | — | — | WO | disclosed |