Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 6/20 | 0.46 |
| ▸ | CNR1 | P21554 | 3/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.43 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.43 |
| ▸ | HCRTR2 | O43614 | 5/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5953869 | 0.87 | ALDH1A1 (0.62) | MAPTHTTMAPK1PPARGPOLB | |
| SCHEMBL20813057 | 0.87 | MAPT (0.47) | MAPTHTTMAPK1CNR2CNR1 | |
| SCHEMBL6486619 | 0.86 | SMN1; SMN2 (0.54) | TSHRCNR2PPARGRAB9AALDH1A1 | |
| SCHEMBL19778187 | 0.83 | NPC1 (0.51) | MAPTHTTTSHRPPARGRAB9A | |
| SCHEMBL19778054 | 0.83 | KMT2A (0.50) | MAPTCNR2CNR1PPARGALDH1A1 | |
| SCHEMBL7845711 | 0.82 | MAPT (0.50) | MAPTHTTRAB9AALDH1A1KDM4E | |
| SCHEMBL28301396 | 0.82 | CYP2C19 (0.61) | MAPTTSHRCNR2CNR1PPARG | |
| SCHEMBL17845859 | 0.81 | ALDH1A1 (0.59) | MAPTMAPK1PPARGPOLBRAB9A | |
| SCHEMBL28703573 | 0.81 | RAB9A (0.45) | MAPTHTTTSHRPOLBRAB9A | |
| SCHEMBL19778056 | 0.81 | PPARG (0.39) | MAPTHTTTSHRMAPK1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109776385-B | Preparation method of N-substituted isatin derivative | 浙江工业大学 | 2020-11-13 | — | — | CN | disclosed |
| CN-109776385-A | A kind of N- replaces the preparation method of Isatine derivatives | 浙江工业大学 | 2019-05-21 | — | — | CN | disclosed |