Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.41 |
| ▸ | MAOB | P27338 | 3/20 | 0.41 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.41 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | FADS1 | O60427 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | EED | O75530 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.31 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.31 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.30 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28876423 | 0.83 | MAOA (0.39) | MAOAMAOBFTOKCNA3ALDH1A1 | |
| SCHEMBL5546709 | 0.79 | MAOA (0.41) | MAOAMAOBFTOKCNA3ALDH1A1 | |
| SCHEMBL29952108 | 0.79 | PTPN1 (0.47) | MAOAMAOBFTOKCNA3ALDH1A1 | |
| SCHEMBL452370 | 0.79 | MAOA (0.41) | MAOAMAOBFTOKCNA3FADS1 | |
| SCHEMBL3800012 | 0.79 | PTPN1 (0.47) | MAOAMAOBFTOKCNA3ALDH1A1 | |
| SCHEMBL9114041 | 0.77 | MAOA (0.33) | MAOAMAOBFTOKCNA3SLC6A2 | |
| SCHEMBL9111374 | 0.76 | KCNA3 (0.36) | MAOAMAOBFTOKCNA3FADS1 | |
| SCHEMBL17873694 | 0.75 | KDM4E (0.39) | MAOAMAOBFTOKCNA3ALDH1A1 | |
| SCHEMBL17863610 | 0.75 | KDM4E (0.39) | MAOAMAOBFTOKCNA3ALDH1A1 | |
| SCHEMBL22409644 | 0.73 | CDK4 (0.43) | MAOAMAOBFTOKCNA3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115232799-A | Styrene monooxygenase mutant and application thereof | 中国科学院成都生物研究所 | 2022-10-25 | — | — | CN | disclosed |
| CN-106542973-B | Ta Simeiqiong intermediate and preparation method thereof | 南京华威医药科技集团有限公司 | 2019-06-25 | — | — | CN | disclosed |