Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28300613 | 0.77 | MAOA (0.41) | MAOAMAOBFTOSLC6A2SLC6A4 | |
| SCHEMBL5546709 | 0.73 | MAOA (0.41) | MAOAMAOBFTOSLC6A2SLC6A4 | |
| SCHEMBL29952108 | 0.70 | PTPN1 (0.47) | MAOAMAOBFTOKCNA3 | |
| SCHEMBL452370 | 0.70 | MAOA (0.41) | MAOAMAOBFTOSLC6A2SLC6A4 | |
| SCHEMBL3800012 | 0.70 | PTPN1 (0.47) | MAOAMAOBFTOKCNA3 | |
| SCHEMBL9113697 | 0.68 | ADRA2A (0.32) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL827076 | 0.67 | GABRA1 (0.43) | MAOAMAOBFTOSLC6A2SLC6A4 | |
| SCHEMBL28876423 | 0.67 | MAOA (0.39) | MAOAMAOBFTOSLC6A2SLC6A4 | |
| SCHEMBL9111374 | 0.67 | KCNA3 (0.36) | MAOAMAOBFTOSLC6A2SLC6A4 | |
| SCHEMBL17873694 | 0.66 | KDM4E (0.39) | MAOAMAOBFTOKCNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0670831-A1 | QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-09-13 | — | — | EP | disclosed |
| WO-1995009159-A1 | QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1995-04-06 | — | — | WO | disclosed |