Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | HPGDS | O60760 | 1/20 | 0.45 |
| ▸ | FYN | P06241 | 2/20 | 0.43 |
| ▸ | KDM5A | P29375 | 1/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.42 |
| ▸ | TUBB | P07437 | 1/20 | 0.42 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.42 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.42 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.42 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.42 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12722869 | 0.75 | PDE10A (0.49) | PDE10AMAPTALDH1A1GAAHPGDS | |
| SCHEMBL12722760 | 0.73 | MAPT (0.51) | NPC1RAB9APDE10AMAPTALDH1A1 | |
| SCHEMBL15557293 | 0.71 | MAPT (0.53) | MAPTGAAKDM4ETSHRNR3C2 | |
| SCHEMBL1438281 | 0.71 | NPC1 (0.54) | NPC1RAB9APDE10AMAPTALDH1A1 | |
| SCHEMBL27310701 | 0.71 | MEN1 (0.51) | NPC1RAB9AMAPTALDH1A1GAA | |
| SCHEMBL28004022 | 0.71 | MAPK9 (0.54) | NPC1RAB9APDE10AALDH1A1KDM5A | |
| SCHEMBL13734610 | 0.71 | ALDH1A1 (0.59) | NPC1RAB9AMAPTALDH1A1MAPK14 | |
| SCHEMBL28300954 | 0.70 | SMN1; SMN2 (0.50) | NPC1RAB9APDE10AMAPTALDH1A1 | |
| SCHEMBL3607497 | 0.70 | MAPK9 (0.57) | NPC1MAPTALDH1A1GAAHPGDS | |
| SCHEMBL13735225 | 0.70 | MAPK9 (0.51) | NPC1RAB9APDE10AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109890822-A | INHIBITORS OF CELLULAR METABOLIC PROCESSES | 安吉奥斯医药品有限公司 | 2019-06-14 | — | — | CN | disclosed |