Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28588455 | 0.88 | MAOA (0.50) | MAOAMAOBMAPKAPK2NPC1LMNA | |
| Ammonia Solution, Strong SCHEMBL21753905 | 0.84 | MAOA (0.43) | MAOAMAOBMAPKAPK2NPC1LMNA | |
| SCHEMBL28299306 | 0.84 | MAOA (0.48) | MAOAMAOBMAPKAPK2NPC1LMNA | |
| SCHEMBL11781450 | 0.72 | MAOA (0.48) | MAOAMAOBMAPKAPK2NPC1LMNA | |
| SCHEMBL27896055 | 0.72 | MAOA (0.48) | MAOAMAOBMAPKAPK2NPC1LMNA | |
| SCHEMBL8655485 | 0.72 | MAOA (0.48) | MAOAMAOBMAPKAPK2NPC1LMNA | |
| SCHEMBL31447550 | 0.72 | MAOA (0.48) | MAOAMAOBMAPKAPK2NPC1LMNA | |
| SCHEMBL149766 | 0.70 | MAOA (0.55) | MAOAMAOBMAPKAPK2 | |
| SCHEMBL30859067 | 0.70 | MAOA (0.55) | MAOAMAOBMAPKAPK2 | |
| SCHEMBL11506362 | 0.70 | MAOA (0.46) | MAOAMAOBMAPKAPK2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109824889-A | The Nomex of structure containing xanthene and its method are prepared based on diiodo- xanthene compound | 江西师范大学 | 2019-05-31 | — | — | CN | disclosed |
| CN-109824889-A | The Nomex of structure containing xanthene and its method are prepared based on diiodo- xanthene compound | 江西师范大学 | 2019-05-31 | — | — | CN | disclosed |