SCHEMBL149766

SCHEMBL149766

c1ccc(-c2cccc3c2Cc2ccccc2O3)cc1

nearest known ligand 0.55

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.55
MAOB P27338 1/20 0.55
PRCP P42785 1/20 0.44
ANPEP P15144 2/20 0.41
IL1RN P18510 1/20 0.41
ERAP2 Q6P179 1/20 0.41
ERAP1 Q9NZ08 1/20 0.41
MAPKAPK2 P49137 1/20 0.40
HTR1A P08908 2/20 0.39
HTR7 P34969 2/20 0.39
THRB P10828 1/20 0.39
KDR P35968 1/20 0.38
ADORA2A P29274 1/20 0.38
ADORA1 P30542 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30859067 1.00 MAOA (0.55) MAOAMAOBPRCPANPEPIL1RN
Hydrochloric Acid SCHEMBL28967142 0.98 MAOA (0.53) MAOAMAOBPRCPANPEPIL1RN
SCHEMBL27773304 0.87 MAOB (0.48) MAOAMAOBMAPKAPK2
SCHEMBL28299306 0.87 MAOA (0.48) MAOAMAOBPRCPANPEPIL1RN
SCHEMBL28252708 0.87 MAOB (0.48) MAOAMAOBPRCPANPEPIL1RN
SCHEMBL15391341 0.87 MAOA (0.48) MAOAMAOBPRCPANPEPIL1RN
SCHEMBL20526412 0.85 MAOA (0.47) MAOAMAOBPRCPANPEPIL1RN
SCHEMBL17482466 0.85 MAOA (0.39) MAOAMAOBPRCPANPEPIL1RN
SCHEMBL2098553 0.84 MAOA (0.46) MAOAMAOBMAPKAPK2ADORA2AADORA1
SCHEMBL11572806 0.83 MAOB (0.44) MAOAMAOBMAPKAPK2HTR1AHTR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 879 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11660057-B2 Systems and methods for persistent ureter visualization STRYKER CORPORATION (US) 2023-05-30 US claimed
EP-3997710-A1 SYSTEMS AND METHODS FOR PERSISTENT URETER VISUALIZATION Stryker Corporation (US) 2022-05-18 EP claimed
EP-3861343-A1 ULTRABRIGHT FLUORESCENT NANOCONSTRUCTS AS UNIVERSAL ENHANCERS Washington University (US) 2021-08-11 EP claimed
US-11077211-B2 Compositions and methods for assessing gut function MEDIBEACON INC. (US) 2021-08-03 US claimed
CN-113167791-A Ultrabright fluorescent nano-constructs as universal enhancers 华盛顿大学 2021-07-23 CN claimed
US-11049906-B2 Imaging device, manufacturing device, and manufacturing method SONY SEMICONDUCTOR SOLUTIONS CORPORATION (JP) 2021-06-29 US claimed
CN-107078143-B Imaging device, manufacturing device and manufacturing method 索尼半导体解决方案公司 2021-06-15 CN claimed
CN-112717146-A Compositions and methods for assessing gut function 麦迪贝肯有限公司 2021-04-30 CN claimed
US-10967096-B2 Tissue sealant compositions, vascular closure devices, and uses thereof MEDIBEACON INC. (US) 2021-04-06 US claimed
US-10960104-B2 Tissue sealant compositions, vascular closure devices, and uses thereof MEDIBEACON INC. (US) 2021-03-30 US claimed
CN-101194380-A Light-emitting element, method for manufacturing light-emitting element, electronic device, and electronic apparatus SEIKO EPSON CORP (JP) 2008-06-04 CN claimed
EP-1854489-A1 Method of measuring physiological function MALLINCKRODT, INC. (US) 2007-11-14 EP claimed
WO-2007106142-A2 PROCESS FOR USING OPTICAL AGENTS MALLINCKRODT INC. (US) 2007-09-20 WO claimed
EP-1642597-A2 Method of measuring physiological function MALLINCKRODT, INC. (US) 2006-04-05 EP claimed
US-20040242902-A1 Labeling Dna in automatic sequencing; bar codes; lipid solubility APPLIED BIOSYSTEMS, INC. 2004-12-02 US claimed
WO-2004101709-A1 PHENYL XANTHENE DYES APPLERA CORPORATION (US) 2004-11-25 WO claimed
EP-1154802-A1 METHOD OF MEASURING PHYSIOLOGICAL FUNCTION Mallinckrodt Inc. (US) 2001-11-21 EP claimed
WO-2000050093-A1 METHOD OF MEASURING PHYSIOLOGICAL FUNCTION MALLINCKRODT INC. (US) 2000-08-31 WO claimed
CN-1039014-C Novel modified oligodeoxynucleotide SANKO CO LTD (JP) 1998-07-08 CN claimed
CN-1098107-A modified oligodeoxynucleotides, their preparation and their therapeutic use SANKYO CO (JP) 1995-02-01 CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11077211-B2 Compositions and methods for assessing gut function FABP2, SLC10A2, SI MAOA 1999/4885MAOB 1763/4885PRCP 1517/4885
US-20040242902-A1 Labeling Dna in automatic sequencing; bar codes; lipid solubility IPO8, BCR, NR1H3 MAOA 3531/4885MAOB 3074/4885PRCP 4546/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.