Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | USP2 | O75604 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | APAF1 | O14727 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | CRHBP | P24387 | 1/20 | 0.51 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.51 |
| ▸ | CNR1 | P21554 | 10/20 | 0.50 |
| ▸ | CNR2 | P34972 | 10/20 | 0.50 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.50 |
| ▸ | GPR55 | Q9Y2T6 | 7/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15396979 | 0.86 | KDM4E (0.52) | MEN1KMT2AKDM4EUSP2HTT | |
| SCHEMBL6109649 | 0.79 | KDM4E (0.59) | MEN1KMT2AKDM4EUSP2HTT | |
| SCHEMBL4282429 | 0.78 | MCL1 (0.49) | CNR1CNR2GPR55 | |
| SCHEMBL45450 | 0.76 | MAOB (0.61) | MEN1KMT2AKDM4EHTTPOLB | |
| SCHEMBL11878333 | 0.75 | SRC (0.58) | MEN1KMT2AKDM4EUSP2HTT | |
| SCHEMBL4527127 | 0.75 | HSD17B3 (0.55) | MEN1KMT2AKDM4EHTTPOLB | |
| SCHEMBL11879786 | 0.75 | KDM4E (0.47) | MEN1KMT2AKDM4EUSP2HTT | |
| SCHEMBL28535264 | 0.75 | MAOB (0.59) | MEN1KMT2AKDM4EUSP2HTT | |
| SCHEMBL21385208 | 0.75 | MAOB (0.59) | MEN1KMT2AKDM4EUSP2HTT | |
| SCHEMBL6136580 | 0.75 | MAOB (0.59) | MEN1KMT2AKDM4EUSP2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109890378-A | FOXO1 activity-inhibiting composition | 三得利控股株式会社 | 2019-06-14 | — | — | CN | disclosed |