Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 9/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | NQO1 | P15559 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 4/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7513873 | 0.80 | GPR55 (0.67) | GPR55MAOA | |
| SCHEMBL28301121 | 0.78 | MEN1 (0.52) | CNR1CNR2GPR55 | |
| SCHEMBL9058086 | 0.77 | MCL1 (0.53) | MCL1ACHENQO1BCHEMAOA | |
| SCHEMBL28374261 | 0.75 | MCL1 (0.55) | MCL1ACHENQO1BCHEMAOA | |
| SCHEMBL18620901 | 0.74 | ADAM17 (0.46) | MCL1ACHENQO1BCHEADAM17 | |
| SCHEMBL17768958 | 0.74 | MCL1 (0.53) | MCL1ACHEBACE1NQO1BCHE | |
| SCHEMBL15179340 | 0.72 | ADAM17 (0.46) | MCL1ACHENQO1BCHEGPR55 | |
| SCHEMBL19686993 | 0.72 | ADAM17 (0.46) | MCL1ACHENQO1BCHEGPR55 | |
| SCHEMBL31344274 | 0.72 | MCL1 (0.47) | MCL1ACHENQO1PDE4D | |
| SCHEMBL67273 | 0.72 | MCL1 (0.47) | MCL1ACHENQO1PDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6693091-B2 | CONTAINING PHOTOACTIVE, FLUORESCENT, OR RADIOACTIVE MOIETY | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | 2004-02-17 | — | — | US | claimed |
| US-20030225052-A1 | Analogs of terpene trilactones from Ginkgo biloba and related compounds and uses thereof | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | 2003-12-04 | — | — | US | claimed |
| US-20030194370-A1 | Analogs of terpene trilactones from ginkgo biloba for bioorganic and imaging studies | THE TRUSTEES OF COLUMBIA UNIVERSITY | 2003-10-16 | — | — | US | claimed |
| WO-2003082185-A2 | ANALOGS OF TERPENE TRILACTONES FROM GINKGO BILOBA AND RELATED COMPOUNDS AND USES THEREOF | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2003-10-09 | — | — | WO | claimed |
| US-20090156668-A1 | Ginkgolide Compounds, Compositions, And Extracts, And Uses Thereof | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2009-06-18 | — | — | US | disclosed |
| US-7473788-B2 | Analogs of terpene trilactones from Ginkgo biloba and related compounds and uses thereof | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2009-01-06 | — | — | US | disclosed |
| US-20070098632-A1 | Analogs of terpene trilactones from ginkgo biloba and related compounds and uses thereof | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | 2007-05-03 | — | — | US | disclosed |
| US-7145021-B2 | Analogs of terpene trilactones from Ginkgo biloba and related compounds and uses thereof | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2006-12-05 | — | — | US | disclosed |
| WO-2005092324-A1 | GINKGOLIDE COMPOUNDS, COMPOSITIONS, EXTRACTS, AND USES THEREOF | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2005-10-06 | — | — | WO | disclosed |
| US-6693091-B2 | CONTAINING PHOTOACTIVE, FLUORESCENT, OR RADIOACTIVE MOIETY | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | 2004-02-17 | — | — | US | disclosed |
| US-20030225052-A1 | Analogs of terpene trilactones from Ginkgo biloba and related compounds and uses thereof | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | 2003-12-04 | — | — | US | disclosed |
| US-20030194370-A1 | Analogs of terpene trilactones from ginkgo biloba for bioorganic and imaging studies | THE TRUSTEES OF COLUMBIA UNIVERSITY | 2003-10-16 | — | — | US | disclosed |
| WO-2003082185-A2 | ANALOGS OF TERPENE TRILACTONES FROM GINKGO BILOBA AND RELATED COMPOUNDS AND USES THEREOF | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2003-10-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070098632-A1 | Analogs of terpene trilactones from ginkgo biloba and related compounds and uses thereof | GRK5, GPR55, GPBAR1 | MCL1 4457/4885ACHE 3397/4885BACE1 3355/4885 |
| US-20030225052-A1 | Analogs of terpene trilactones from Ginkgo biloba and related compounds and uses thereof | GPBAR1, GRK5, CNR1 | MCL1 4327/4885ACHE 3082/4885BACE1 2856/4885 |
| US-20090156668-A1 | Ginkgolide Compounds, Compositions, And Extracts, And Uses Thereof | PYGB, NLN, GRIN3B | MCL1 2110/4885ACHE 569/4885BACE1 424/4885 |
| US-20030194370-A1 | Analogs of terpene trilactones from ginkgo biloba for bioorganic and imaging studies | GRK4, GRK1, GNB1 | MCL1 3789/4885ACHE 3016/4885BACE1 1898/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.