SCHEMBL45450

SCHEMBL45450

CCCCCc1cc2ccccc2oc1=O

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 3/20 0.61
MAOA P21397 3/20 0.61
MMP2 P08253 1/20 0.56
MMP9 P14780 1/20 0.56
ADAM17 P78536 1/20 0.56
LMNA P02545 2/20 0.51
MAPT P10636 2/20 0.51
CNR1 P21554 1/20 0.48
CNR2 P34972 1/20 0.48
KDM4E B2RXH2 3/20 0.48
ALDH1A1 P00352 1/20 0.48
SMN1; SMN2 Q16637 3/20 0.47
HPGD P15428 2/20 0.47
POLB P06746 2/20 0.47
TYR P14679 1/20 0.47
DAO P14920 1/20 0.47
AKR1B1 P15121 1/20 0.47
MEN1 O00255 2/20 0.47
HTT P42858 2/20 0.47
KMT2A Q03164 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6136580 0.98 MAOB (0.59) MAOBMAOAMMP2MMP9ADAM17
SCHEMBL28535264 0.98 MAOB (0.59) MAOBMAOAMMP2MMP9ADAM17
SCHEMBL21385208 0.98 MAOB (0.59) MAOBMAOAMMP2MMP9ADAM17
SCHEMBL3506842 0.95 MAOB (0.62) MAOBMAOAMMP2MMP9ADAM17
Thiophene SCHEMBL27776643 0.92 MAOB (0.53) MAOBMAOAMMP2MMP9ADAM17
SCHEMBL11092927 0.89 MAOB (0.66) MAOBMAOAMMP2MMP9ADAM17
SCHEMBL6136579 0.85 MAOB (0.47) MAOBMAOAMMP2MMP9ADAM17
SCHEMBL27625488 0.85 MMP2 (0.67) MAOBMAOAMMP2MMP9ADAM17
SCHEMBL293427 0.84 MMP2 (0.56) MAOBMAOAMMP2MMP9ADAM17
SCHEMBL1619109 0.83 MAOB (0.67) MAOBMAOAMMP2MMP9ADAM17

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1290 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117926632-A High-bulk composite white cardboard and manufacturing method thereof 昆明小松制版印刷有限公司 2024-04-26 CN claimed
CN-114805272-B Arylcoumarin probe, probe molecule complex and Hg of urban sewage planning system 2+ Application in detection 济南市规划设计研究院 2024-04-16 CN claimed
CN-116990401-A Method for analyzing three-white soup ingredients by using ultrahigh resolution liquid chromatography-mass spectrometry technology 安徽中医药大学 2023-11-03 CN claimed
CN-115057840-B Synthesis method of 3-acyl coumarin compound promoted by visible light 湖南理工学院 2023-09-26 CN claimed
CN-109651320-B Synthesis method of 2-aryl benzopyrone flavone derivatives 黑龙江大学(CN) 2023-01-13 CN claimed
US-20230012268-A1 COMPOSITIONS AND METHODS FOR TREATMENT OF INFLAMMATION WITH STEROIDS AND A MODULATOR BUZZELET DEVELOPMENT AND TECHNOLOGIES LTD (IL) 2023-01-12 US claimed
CN-115057840-A Synthesis method of 3-acylcoumarin compound promoted by visible light 湖南理工学院 2022-09-16 CN claimed
CN-113797195-B Application of 3-aryl coumarin compound, anti-cancer sensitization composition and anti-cancer composition 山东第一医科大学(山东省医学科学院) 2022-09-13 CN claimed
CN-114805272-A Aryl coumarin probe, probe molecule compound and Hg in urban planning sewage system 2+ Applications in assays 济南市规划设计研究院 2022-07-29 CN claimed
CN-113797195-A Application of 3-aryl coumarin compound, anti-cancer sensitization composition and anti-cancer composition 山东第一医科大学(山东省医学科学院) 2021-12-17 CN claimed
WO-2008096354-A2 MEANS AND METHODS OF PRODUCING FRUITS WITH HIGH LEVELS OF ANTHOCYANINS AND FLAVONOLS THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION, (A.R.O.), THE VOLCANL CENTER (IL) 2008-08-14 WO claimed
US-20050014819-A1 Peroxisome proliferator activated receptor ligands and process for producing the same KANEKA CORPORATION (JP) 2005-01-20 US claimed
EP-1440688-A1 PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR LIGANDS AND PROCESS FOR PRODUCING THE SAME KANEKA CORPORATION (JP) 2004-07-28 EP claimed
US-20040071745-A1 Admixture of carotenoids and isoflavonoids for treating cutaneous symptoms of aging SOCIETE L'OREAL S.A. (FR) 2004-04-15 US claimed
US-20020197289-A1 Compositions and methods for combating the appearance of ageing L'OREAL (FR) 2002-12-26 US claimed
US-5554663-A α-aminoacetophenones as photoinitiators CIBA-GEIGY CORPORATION (US) 1996-09-10 US claimed
EP-0284561-B1 ALPHA-AMINOACETOPHENONES AS PHOTO INITIATORS CIBA-GEIGY AG (CH) 1993-05-12 EP claimed
EP-0138754-B1 PHOTOCURABLE COMPOSITIONS CIBA-GEIGY AG (CH) 1988-05-25 EP claimed
EP-0022188-B1 CO-INITIATOR COMPOSITIONS FOR PHOTOPOLYMERIZATION CONTAINING 3-ACYL-SUBSTITUTED COUMARINS, PHOTOPOLYMERIZABLE COMPOSITION AND PHOTOGRAPHIC ELEMENT EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1984-10-03 EP claimed
US-4404300-A Polystyrene process POLYSAR LIMITED (CA) 1983-09-13 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020197289-A1 Compositions and methods for combating the appearance of ageing CYP24A1, CYP27B1, CYP2R1 MAOB 18/4885MAOA 53/4885MMP2 297/4885
US-20050014819-A1 Peroxisome proliferator activated receptor ligands and process for producing the same PPARG, PPARA, PPARD MAOB 4716/4885MAOA 4792/4885MMP2 3608/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.