SCHEMBL28301261

SCHEMBL28301261

CCCCCC=CC=CCNCCCCC

nearest known ligand 0.55

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.55
TSHR P16473 2/20 0.55
KDM1A O60341 5/20 0.48
FASN P49327 1/20 0.44
FAAH O00519 6/20 0.43
TRPV1 Q8NER1 1/20 0.43
CNR1 P21554 2/20 0.42
CNR2 P34972 2/20 0.42
PPARA Q07869 2/20 0.42
EPHX1 P07099 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9205985 0.87 KDM1A (0.58) ALDH1A1TSHRKDM1AFAAHTRPV1
SCHEMBL2203534 0.85 ALDH1A1 (0.42) ALDH1A1TSHRKDM1AFASNFAAH
SCHEMBL29077674 0.85 KDM1A (0.61) ALDH1A1TSHRKDM1AFAAHTRPV1
SCHEMBL22814017 0.80 TRPV1 (0.55) ALDH1A1TSHRFAAHTRPV1
SCHEMBL24363508 0.79 KDM1A (0.48) ALDH1A1TSHRKDM1AEPHX1
SCHEMBL4929983 0.79 TSHR (0.71) ALDH1A1TSHRFASNFAAHTRPV1
SCHEMBL4929989 0.79 TSHR (0.71) ALDH1A1TSHRFASNFAAHTRPV1
SCHEMBL23911885 0.79 ALDH1A1 (0.50) ALDH1A1TSHRFASNFAAHTRPV1
SCHEMBL7037260 0.79 PPARA (0.50) ALDH1A1TSHRKDM1AFAAHTRPV1
SCHEMBL24131906 0.78 KDM1A (0.58) ALDH1A1TSHRKDM1AFAAHTRPV1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109996778-A Taste adjusts aldehyde 高砂香料工业株式会社 2019-07-09 CN disclosed