Isobutylbenzene

Isobutylbenzene

SCHEMBL28301265

CC(C)Cc1ccccc1.CCC(C)c1ccccc1

nearest known ligand 0.68

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Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 2/20 0.48
SIGMAR1 Q99720 3/20 0.47
TAAR1 Q96RJ0 5/20 0.47
SLC6A2 P23975 2/20 0.47
MAOA P21397 1/20 0.47
SLC6A4 P31645 1/20 0.47
SLC6A3 Q01959 1/20 0.47
CYP2A6 P11509 1/20 0.47
ADORA2A P29274 1/20 0.47
ADORA1 P30542 1/20 0.47
ALOX5 P09917 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4443642 0.85 TAAR1 (0.61) TRPA1TAAR1
SCHEMBL17453236 0.85 TAAR1 (0.61) TRPA1TAAR1
Benzene SCHEMBL5290987 0.85 TAAR1 (0.61) TRPA1TAAR1
SCHEMBL136376 0.85 TAAR1 (0.61) TRPA1TAAR1
Hydrogen Peroxide SCHEMBL11692595 0.83 TRPA1 (0.61) TRPA1TAAR1
Methane SCHEMBL28848997 0.83 TAAR1 (0.58) TRPA1TAAR1
Hydrogen Peroxide SCHEMBL190109 0.83 TRPA1 (0.61) TRPA1TAAR1
Ammonia Solution, Strong SCHEMBL6014467 0.83 TAAR1 (0.58) TRPA1TAAR1
SCHEMBL31498533 0.83 TAAR1 (0.58) TRPA1TAAR1
Water SCHEMBL27860324 0.83 TAAR1 (0.58) TRPA1TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109759127-A A kind of preparation method for isobutene and the hollow monocrystalline Beta molecular sieve catalyst of benzene liquid-phase alkylation 中国科学院大连化学物理研究所 2019-05-17 CN disclosed