Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 3/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.40 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | BID | P55957 | 5/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 5/20 | 0.37 |
| ▸ | BCL2L1 | Q07817 | 4/20 | 0.37 |
| ▸ | BAK1 | Q16611 | 4/20 | 0.37 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.37 |
| ▸ | PPARG | P37231 | 2/20 | 0.37 |
| ▸ | EP300 | Q09472 | 1/20 | 0.37 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.37 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.37 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.37 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.37 |
| ▸ | KDM5A | P29375 | 1/20 | 0.37 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL311774 | 0.89 | POLB (0.41) | PPARAMTNR1ASLC13A5POLBTDP1 | |
| SCHEMBL28118987 | 0.78 | KDM4E (0.39) | PPARAPTPN1PTPN11MTNR1APPARG | |
| SCHEMBL27782514 | 0.78 | PTPN1 (0.42) | PPARAPTPN1PTPN11BIDMCL1 | |
| SCHEMBL7042463 | 0.76 | CA12 (0.57) | PPARAPOLBTDP1CA12CA1 | |
| SCHEMBL14806688 | 0.76 | HPGD (0.42) | SLC13A5 | |
| SCHEMBL30639556 | 0.75 | POLB (0.43) | MTNR1ASLC13A5POLBTDP1MCL1 | |
| SCHEMBL27032969 | 0.75 | POLB (0.43) | MTNR1ASLC13A5POLBTDP1MCL1 | |
| SCHEMBL12794738 | 0.75 | POLB (0.43) | MTNR1ASLC13A5POLBTDP1KDM5A | |
| SCHEMBL5069502 | 0.75 | ALDH1A1 (0.35) | MTNR1ASLC13A5MTNR1B | |
| SCHEMBL2098279 | 0.74 | POLB (0.41) | MTNR1ASLC13A5POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109996546-A | P2X3And/or P2X2/3Compounds and methods | 阿沙纳生物科学公司 | 2019-07-09 | — | — | CN | disclosed |