Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 13/20 | 0.33 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13234061 | 0.89 | MMP12 (0.31) | NAAA | |
| SCHEMBL27934842 | 0.78 | EPHX1 (0.39) | EPHX1ACHE | |
| SCHEMBL11100479 | 0.77 | EPHX1 (0.52) | EPHX1ACHE | |
| SCHEMBL17393935 | 0.77 | ACHE (0.44) | EPHX1ACHE | |
| Ammonia Solution, Strong SCHEMBL27626603 | 0.76 | EPHX1 (0.50) | EPHX1ACHE | |
| SCHEMBL21059108 | 0.76 | EPHX1 (0.60) | NAAAEPHX1ACHE | |
| SCHEMBL29148821 | 0.76 | EPHX1 (0.37) | EPHX1ACHE | |
| SCHEMBL28313907 | 0.76 | EPHX1 (0.37) | EPHX1ACHE | |
| SCHEMBL12057397 | 0.76 | EPHX1 (0.37) | EPHX1ACHE | |
| SCHEMBL13278329 | 0.76 | ACHE (0.51) | EPHX1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109897011-A | A kind of IDO inhibitor and its application | 上海华汇拓医药科技有限公司 | 2019-06-18 | — | — | CN | disclosed |
| CN-104487431-A | Novel indazoles for the treatment and prophylaxis of respiratory syncytial virus infection | HOFFMANN LA ROCHE | 2015-04-01 | — | — | CN | disclosed |