Acrylic Acid

Acrylic Acid

SCHEMBL28301528

C=C(CCCC)C(=O)OO.C=CC(=O)O

nearest known ligand 0.39

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 8/20 0.39
HPGD P15428 1/20 0.39
ALOX15 P16050 2/20 0.37
HSD17B10 Q99714 2/20 0.37
LMNA P02545 1/20 0.36
CES2 O00748 1/20 0.35
CES1 P23141 1/20 0.35
ALDH1A1 P00352 3/20 0.33
HCAR2 Q8TDS4 2/20 0.33
AKR1B1 P15121 1/20 0.33
TP53 P04637 1/20 0.33
ZDHHC20 Q5W0Z9 1/20 0.33
ZDHHC2 Q9UIJ5 1/20 0.33
PPARG P37231 4/20 0.32
PPARD Q03181 4/20 0.32
PPARA Q07869 4/20 0.32
GPR84 Q9NQS5 3/20 0.32
HDAC11 Q96DB2 3/20 0.32
TDP1 Q9NUW8 2/20 0.32
SLC22A6 Q4U2R8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Propene SCHEMBL28322952 0.89 CES1 (0.38) TSHRHPGDCES2CES1ALDH1A1
SCHEMBL198129 0.89 CES1 (0.44) TSHRALOX15HSD17B10CES2CES1
Hydrochloric Acid SCHEMBL16599967 0.87 CES1 (0.42) TSHRALOX15HSD17B10CES2CES1
Acrylic Acid SCHEMBL28099761 0.86 ALOX15 (0.41) TSHRHPGDALOX15HSD17B10LMNA
SCHEMBL7028156 0.85 CES1 (0.41) TSHRCES2CES1ALDH1A1AKR1B1
Acrylic Acid SCHEMBL20680727 0.83 TSHR (0.53) TSHRHPGDALOX15HSD17B10CES2
SCHEMBL891395 0.83 CES2 (0.46) TSHRALOX15HSD17B10CES2CES1
Acrylic Acid SCHEMBL27398374 0.81 TSHR (0.36) TSHRHPGDALOX15HSD17B10LMNA
Acrylic Acid SCHEMBL2126766 0.81 ALOX15 (0.52) TSHRHPGDALOX15HSD17B10LMNA
Acrylic Acid SCHEMBL29726247 0.81 ALOX15 (0.52) TSHRHPGDALOX15HSD17B10LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110023420-A Resinous, curing system and the floor paint of diamond particles and preparation method thereof AFI特许有限责任公司 2019-07-16 CN disclosed