Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 1/20 | 0.53 |
| ▸ | HPGDS | O60760 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.47 |
| ▸ | JAK1 | P23458 | 1/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.44 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.44 |
| ▸ | FPR2 | P25090 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20748135 | 1.00 | PDE4B (0.53) | PDE4BHPGDSALDH1A1MEN1MAPT | |
| SCHEMBL18937651 | 0.93 | PDE4B (0.60) | PDE4BHPGDSMAPTNAMPTESR2 | |
| SCHEMBL18509294 | 0.89 | GPR119 (0.54) | PDE4BHPGDSALDH1A1MEN1MAPT | |
| SCHEMBL12279408 | 0.88 | MEN1 (0.57) | PDE4BMEN1KMT2AHSD11B1LMNA | |
| SCHEMBL22810473 | 0.88 | PDE4B (0.52) | PDE4BHPGDSALDH1A1MEN1MAPT | |
| SCHEMBL1422394 | 0.88 | PDE4B (0.52) | PDE4BHPGDSALDH1A1MEN1MAPT | |
| SCHEMBL1673620 | 0.88 | FPR2 (0.55) | PDE4BHPGDSALDH1A1MEN1MAPT | |
| SCHEMBL18557979 | 0.88 | FPR2 (0.55) | PDE4BHPGDSALDH1A1MEN1MAPT | |
| SCHEMBL28943526 | 0.88 | FPR2 (0.55) | PDE4BHPGDSALDH1A1MEN1MAPT | |
| SCHEMBL1988650 | 0.88 | PDE4B (0.52) | PDE4BHPGDSALDH1A1MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109810047-A | (R) synthetic method of the chiral intermediate of -3- Phenylpiperidine or/and (S) -3- Phenylpiperidine and Ni Lapani | 上海博邦医药科技有限公司 | 2019-05-28 | — | — | CN | disclosed |