Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | DPP4 | P27487 | 2/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27660598 | 0.87 | ATM (0.38) | ADRA2AADRA2CLMNAHIF1AKDM4E | |
| SCHEMBL5650824 | 0.87 | ATM (0.38) | ADRA2AADRA2CLMNAHIF1AKDM4E | |
| SCHEMBL5652634 | 0.87 | ATM (0.38) | ADRA2AADRA2CLMNAHIF1AKDM4E | |
| SCHEMBL6896070 | 0.84 | DPP4 (0.43) | ADRA2AADRA2CLMNAHIF1AKDM4E | |
| SCHEMBL15630763 | 0.84 | DPP4 (0.43) | ADRA2AADRA2CLMNAHIF1AKDM4E | |
| SCHEMBL27892297 | 0.83 | AAK1 (0.36) | ATML3MBTL1DPP4AOC3NPSR1 | |
| SCHEMBL14625079 | 0.83 | KMT2A (0.53) | ADRA2AADRA2CLMNAHIF1AKDM4E | |
| SCHEMBL10699210 | 0.83 | DPP4 (0.42) | ADRA2AADRA2CLMNAHIF1AKDM4E | |
| SCHEMBL1624875 | 0.81 | DPP4 (0.48) | ATML3MBTL1ALDH1A1DPP4AOC3 | |
| SCHEMBL9833387 | 0.80 | ALDH1A1 (0.41) | ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109943542-A | A kind of alcohol dehydrogenase for the production of atazanavir intermediate | 南京诺云生物科技有限公司 | 2019-06-28 | — | — | CN | disclosed |
| CN-109943577-A | A kind of bioconversion method of anti-AIDS drug atazanavir intermediate | 南京诺云生物科技有限公司 | 2019-06-28 | — | — | CN | disclosed |