Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | REN | P00797 | 7/20 | 0.39 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.39 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.37 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27613187 | 0.89 | F10 (0.40) | ALDH1A1 | |
| SCHEMBL27765142 | 0.85 | MAPT (0.37) | ALDH1A1KLK5 | |
| SCHEMBL27892297 | 0.83 | AAK1 (0.36) | CTSSCTSKLTA4H | |
| SCHEMBL20645798 | 0.81 | ALDH1A1 (0.48) | ALDH1A1ABCB1KCNA5KMT2A | |
| SCHEMBL14205038 | 0.81 | ALDH1A1 (0.48) | ALDH1A1ABCB1KCNA5KMT2A | |
| SCHEMBL8069348 | 0.80 | ALDH1A1 (0.40) | ALDH1A1CTSSCTSKITGA4ITGB7 | |
| SCHEMBL28301558 | 0.80 | ADRA2A (0.40) | ALDH1A1KMT2A | |
| SCHEMBL5650824 | 0.79 | ATM (0.38) | KMT2ACTSSCTSKLTA4H | |
| SCHEMBL5652634 | 0.79 | ATM (0.38) | KMT2ACTSSCTSKLTA4H | |
| SCHEMBL27660598 | 0.79 | ATM (0.38) | ALDH1A1KMT2ACTSSCTSKLTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026642-A | Process for the enzymatic production of ketones | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-06-25 | — | — | US | disclosed |