SCHEMBL28301560

SCHEMBL28301560

CC(C)(C)OC(=O)C(Cc1ccccc1)C(O)CN

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ITGA4 P13612 2/20 0.45
ITGB7 P26010 2/20 0.45
KLK5 Q9Y337 2/20 0.45
ATM Q13315 1/20 0.43
SLC1A3 P43003 1/20 0.43
SLC1A2 P43004 1/20 0.43
SLC1A1 P43005 1/20 0.43
MAPT P10636 2/20 0.42
POLB P06746 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
CTSS P25774 2/20 0.41
CTSL P07711 1/20 0.41
CTSB P07858 1/20 0.41
CTSK P43235 1/20 0.41
LTA4H P09960 1/20 0.41
SLC7A5 Q01650 2/20 0.41
ACE P12821 1/20 0.40
SRR Q9GZT4 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5016667 0.85 SLC1A3 (0.49) ITGA4ITGB7KLK5ATMSLC1A3
SCHEMBL6703242 0.85 SLC1A3 (0.49) ITGA4ITGB7KLK5ATMSLC1A3
SCHEMBL8019635 0.84 ITGA4 (0.48) ITGA4ITGB7KLK5ATMSLC1A3
SCHEMBL4669804 0.83 SLC1A3 (0.44) ITGA4ITGB7KLK5ATMSLC1A3
SCHEMBL8486317 0.83 SLC1A3 (0.44) ITGA4ITGB7KLK5ATMSLC1A3
SCHEMBL28295654 0.83 SLC1A3 (0.44) ITGA4ITGB7KLK5ATMSLC1A3
SCHEMBL27292012 0.82 ITGA4 (0.43) ITGA4ITGB7KLK5ATMMAPT
SCHEMBL15015724 0.82 SLC1A3 (0.51) ITGA4ITGB7ATMSLC1A3SLC1A2
SCHEMBL20805059 0.82 ITGA4 (0.49) ITGA4ITGB7KLK5ATMSLC1A3
SCHEMBL7280316 0.82 SLC1A3 (0.51) ITGA4ITGB7ATMSLC1A3SLC1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109943542-A A kind of alcohol dehydrogenase for the production of atazanavir intermediate 南京诺云生物科技有限公司 2019-06-28 CN disclosed
CN-109943577-A A kind of bioconversion method of anti-AIDS drug atazanavir intermediate 南京诺云生物科技有限公司 2019-06-28 CN disclosed