Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 1/20 | 0.44 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.44 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.44 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.44 |
| ▸ | ITGB7 | P26010 | 2/20 | 0.44 |
| ▸ | LTA4H | P09960 | 2/20 | 0.42 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ALPI | P09923 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | XIAP | P98170 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 2/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28295654 | 1.00 | SLC1A3 (0.44) | SLC1A3SLC1A2SLC1A1ITGA4ITGB7 | |
| SCHEMBL8486317 | 1.00 | SLC1A3 (0.44) | SLC1A3SLC1A2SLC1A1ITGA4ITGB7 | |
| SCHEMBL5016667 | 0.86 | SLC1A3 (0.49) | SLC1A3SLC1A2SLC1A1ITGA4ITGB7 | |
| SCHEMBL6703242 | 0.86 | SLC1A3 (0.49) | SLC1A3SLC1A2SLC1A1ITGA4ITGB7 | |
| SCHEMBL9833389 | 0.84 | ITGA4 (0.47) | SLC1A3SLC1A2SLC1A1ITGA4ITGB7 | |
| SCHEMBL28301560 | 0.83 | ITGA4 (0.45) | SLC1A3SLC1A2SLC1A1ITGA4ITGB7 | |
| SCHEMBL27613188 | 0.83 | SLC1A3 (0.44) | SLC1A3SLC1A2SLC1A1ITGA4ITGB7 | |
| SCHEMBL8069353 | 0.82 | ITGA4 (0.45) | SLC1A3SLC1A2SLC1A1ITGA4ITGB7 | |
| SCHEMBL27773551 | 0.82 | SLC1A1 (0.64) | SLC1A3SLC1A2SLC1A1ITGA4ITGB7 | |
| SCHEMBL27608532 | 0.82 | SLC1A3 (0.47) | SLC1A3SLC1A2SLC1A1ITGA4ITGB7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1792986-B1 | NOVEL CARBONYL REDUCTASE, GENE THEREOF AND METHOD OF USING THE SAME | KANEKA CORP (JP) | 2008-12-31 | — | — | EP | claimed |