Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.49 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.49 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.48 |
| ▸ | SLC6A1 | P30531 | 1/20 | 0.44 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.44 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | CCR1 | P32246 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19226368 | 0.83 | OPRM1 (0.58) | OPRM1OPRD1OPRK1OPRL1HSD11B1 | |
| SCHEMBL19462825 | 0.82 | OPRM1 (0.43) | OPRM1OPRD1OPRK1OPRL1HSD11B1 | |
| SCHEMBL12363963 | 0.82 | OPRM1 (0.51) | OPRM1OPRD1OPRK1OPRL1HSD11B1 | |
| Hydrochloric Acid SCHEMBL10752401 | 0.81 | OPRM1 (0.50) | OPRM1OPRD1OPRK1OPRL1HSD11B1 | |
| SCHEMBL10319703 | 0.79 | OPRM1 (0.55) | OPRM1OPRD1OPRK1OPRL1HSD11B1 | |
| SCHEMBL12317609 | 0.79 | OPRM1 (0.55) | OPRM1OPRD1OPRK1OPRL1HSD11B1 | |
| SCHEMBL28970507 | 0.78 | SLC6A4 (0.54) | OPRM1OPRD1OPRK1OPRL1HSD11B1 | |
| SCHEMBL2778410 | 0.78 | SLC6A4 (0.54) | OPRM1OPRD1OPRK1OPRL1HSD11B1 | |
| SCHEMBL21874209 | 0.78 | SLC6A4 (0.54) | OPRM1OPRD1OPRK1OPRL1HSD11B1 | |
| SCHEMBL28970493 | 0.78 | SLC6A4 (0.54) | OPRM1OPRD1OPRK1OPRL1HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109810047-A | (R) synthetic method of the chiral intermediate of -3- Phenylpiperidine or/and (S) -3- Phenylpiperidine and Ni Lapani | 上海博邦医药科技有限公司 | 2019-05-28 | — | — | CN | disclosed |