Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDO2 | P48775 | 6/20 | 0.60 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.51 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.51 |
| ▸ | IDO1 | P14902 | 2/20 | 0.47 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | HTR5A | P47898 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | GABRP | O00591 | 2/20 | 0.45 |
| ▸ | GABRD | O14764 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.45 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.45 |
| ▸ | MAOA | P21397 | 2/20 | 0.45 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.45 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28301576 | 0.92 | TDO2 (0.58) | TDO2CYP11B1CYP11B2IDO1LRRK2 | |
| SCHEMBL28938781 | 0.84 | TDO2 (0.59) | TDO2CYP11B1CYP11B2IDO1LRRK2 | |
| SCHEMBL148203 | 0.84 | TDO2 (0.65) | TDO2CYP11B1CYP11B2IDO1LRRK2 | |
| SCHEMBL29572015 | 0.84 | TDO2 (0.65) | TDO2CYP11B1CYP11B2IDO1LRRK2 | |
| SCHEMBL30353781 | 0.81 | CYP11B1 (0.57) | TDO2CYP11B1CYP11B2IDO1LRRK2 | |
| SCHEMBL148467 | 0.80 | TDO2 (0.54) | TDO2CYP11B1CYP11B2IDO1LRRK2 | |
| SCHEMBL193017 | 0.80 | ESR1 (0.52) | TDO2HTR2BHTR5AKDM4EGABRP | |
| SCHEMBL30022621 | 0.80 | ESR1 (0.52) | TDO2HTR2BHTR5AKDM4EGABRP | |
| Ammonia Solution, Strong SCHEMBL14343305 | 0.79 | ESR1 (0.50) | TDO2HTR2BHTR5AKDM4EGABRP | |
| SCHEMBL30302859 | 0.79 | ESR1 (0.50) | TDO2HTR2BHTR5AKDM4EGABRP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109790117-A | Carbazole benzene class fused-ring derivatives, polymer, mixture, composition, organic electronic device and preparation method thereof | 广州华睿光电材料有限公司 | 2019-05-21 | — | — | CN | disclosed |
| CN-104560012-A | Bipolar blue-light phosphorescent compound, preparation method thereof and organic electroluminescent device | OCEANS KING LIGHTING SCIENCE | 2015-04-29 | — | — | CN | disclosed |