SCHEMBL28301628

SCHEMBL28301628

O=C(O)c1ccc2ccnc-2[nH]1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIN1 Q13526 3/20 0.58
KDM4E B2RXH2 5/20 0.47
ALDH1A1 P00352 4/20 0.47
USP2 O75604 1/20 0.44
HPGD P15428 1/20 0.44
HSD17B10 Q99714 1/20 0.44
KDM6B O15054 1/20 0.41
TET3 O43151 1/20 0.41
KDM4A O75164 1/20 0.41
BBOX1 O75936 1/20 0.41
MAPT P10636 1/20 0.41
KDM5A P29375 1/20 0.41
KDM5C P41229 1/20 0.41
ASPH Q12797 1/20 0.41
KDM4D Q6B0I6 1/20 0.41
TET2 Q6N021 1/20 0.41
ALKBH5 Q6P6C2 1/20 0.41
KDM7A Q6ZMT4 1/20 0.41
KDM8 Q8N371 1/20 0.41
TET1 Q8NFU7 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19463621 0.83 PIN1 (0.43) PIN1KDM4EALDH1A1MAPK13
SCHEMBL28303090 0.79 KDM4E (0.54) PIN1KDM4EALDH1A1HPGDKDM6B
SCHEMBL3057838 0.73 PIN1 (1.00) PIN1CYP1A2MAPK1CASP1CYP2C19
SCHEMBL17868506 0.73 PIN1 (0.72) PIN1KDM4EALDH1A1USP2HPGD
SCHEMBL14953213 0.73 PIN1 (0.72) PIN1KMONPY5RMAPK14
SCHEMBL7699701 0.73 PIN1 (0.72) PIN1KDM4EALDH1A1MAPTALKBH5
SCHEMBL17868429 0.73 PIN1 (0.72) PIN1KDM4EALDH1A1HPGDHSD17B10
SCHEMBL8816338 0.72 PIN1 (0.43) PIN1KDM4EALDH1A1KDM6BTET3
SCHEMBL2022196 0.72 PIN1 (0.47) PIN1KDM4EALDH1A1USP2HPGD
Hydrochloric Acid SCHEMBL27325075 0.72 PIN1 (0.70) PIN1KDM4EALDH1A1USP2HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025090827-A1 A1AT MODULATORS SUB21, INC. (US) 2025-05-01 WO disclosed
EP-4175634-A4 SOLID FORMS OF (Z)-METHYL 3-(((4-(N-METHYL-2-(4-METHYLPIPERAZIN-L- YL)ACETAMIDO)PHENYL)AMINO)(PHENYL)METHYLENE)-2-OXO-2, 3-DIHYDRO- LH-PYRROLO[2,3-B]PYRIDINE-6-CARBOXYLATE AND SALTS THEREOF Angion Biomedica Corp. (US) 2024-08-21 EP disclosed
EP-4175634-A1 SOLID FORMS OF (Z)-METHYL 3-(((4-(N-METHYL-2-(4-METHYLPIPERAZIN-L- YL)ACETAMIDO)PHENYL)AMINO)(PHENYL)METHYLENE)-2-OXO-2, 3-DIHYDRO- LH-PYRROLO[2,3-B]PYRIDINE-6-CARBOXYLATE AND SALTS THEREOF Angion Biomedica Corp. (US) 2023-05-10 EP disclosed
WO-2023009330-A1 SEROTONIN 5-HT2B INHIBITORY COMPOUNDS ZOETIS SERVICES LLC (US) 2023-02-02 WO disclosed
CN-110003169-A GPR40 receptor agonist, method for preparing same, and pharmaceutical composition containing same as active ingredient 株式会社LG化学 2019-07-12 CN disclosed
CN-109952302-A Muscarine M1 receptor forward direction allosteric modulators 苏文生命科学有限公司 2019-06-28 CN disclosed