Phenol

Phenol

SCHEMBL28301641

CC(C)Cc1ccc(CC(C)C)c(CC(C)C)c1.Oc1ccccc1

nearest known ligand 0.61

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 2/20 0.61
GABRB2 P47870 2/20 0.61
TAAR1 Q96RJ0 3/20 0.39
SLC6A2 P23975 2/20 0.39
PTGS2 P35354 4/20 0.39
ESR1 P03372 4/20 0.39
PTGS1 P23219 3/20 0.39
LMNA P02545 3/20 0.39
CYP2C9 P11712 3/20 0.39
AKR1C3 P42330 2/20 0.39
CXCR1 P25024 2/20 0.39
CXCR2 P25025 2/20 0.39
ALOX5 P09917 2/20 0.39
NFKB1 P19838 2/20 0.39
HTR2A P28223 2/20 0.39
BLM P54132 2/20 0.39
PMP22 Q01453 2/20 0.39
ALB P02768 1/20 0.39
RARB P10826 1/20 0.39
ADRB3 P13945 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenol SCHEMBL28329970 0.82 GABRA1 (0.48) GABRA1GABRB2TAAR1SLC6A2GLA
Phenol SCHEMBL28093153 0.81 CA12 (0.48) GABRA1GABRB2TAAR1SLC6A2PTGS2
Isobutylbenzene SCHEMBL28090069 0.79 TAAR1 (0.52) TAAR1SLC6A2PTGS2ESR1PTGS1
Phenol SCHEMBL28225282 0.79 GABRA1 (0.42) GABRA1GABRB2TAAR1SLC6A2PTGS2
SCHEMBL5053439 0.77 GABRA1 (0.62) GABRA1GABRB2SLC6A2PTGS2ESR1
SCHEMBL318750 0.76 GABRA1 (1.00) GABRA1GABRB2SLC6A2PTGS2ESR1
SCHEMBL2292664 0.76 GABRA1 (0.71) GABRA1GABRB2SLC6A2PTGS2ESR1
SCHEMBL9734205 0.75 GABRA1 (0.50) GABRA1GABRB2TAAR1SLC6A2ESR1
Hydrogen Peroxide SCHEMBL5685702 0.74 GABRA1 (0.65) GABRA1GABRB2TAAR1SLC6A2PTGS2
SCHEMBL677750 0.74 GABRA1 (0.58) GABRA1GABRB2SLC6A2PTGS2ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109929103-A A kind of manufacturing method of high inherent viscosity polyphenylene oxide 埃得新材料有限公司 2019-06-25 CN disclosed