SCHEMBL28301668

SCHEMBL28301668

CN1CCCCC1C=O.O=C1CC1O

nearest known ligand 0.47

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CHRM1 P11229 5/20 0.45
CHRM2 P08172 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12018255 0.85
SCHEMBL88583 0.85
SCHEMBL14087966 0.85
SCHEMBL18967338 0.83 CHRM1 (0.45) CHRM1CHRM2
SCHEMBL2089060 0.79
SCHEMBL327784 0.79
SCHEMBL1299627 0.79
Iodide SCHEMBL38651116 0.77
SCHEMBL2089866 0.70
SCHEMBL31029450 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109810110-A A kind of compound with 2- aminopyrimidine structure, preparation method and use 中国科学院上海药物研究所 2019-05-28 CN disclosed