Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPKAPK2 | P49137 | 4/20 | 0.53 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.51 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | KDR | P35968 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.44 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5319319 | 0.91 | MAPKAPK2 (0.60) | MAPKAPK2MAPK9MAPK10MEN1ALDH1A1 | |
| Benzene SCHEMBL27839441 | 0.87 | MAPK9 (0.54) | MAPK9MAPK10KDRCYP1A2CYP3A4 | |
| SCHEMBL528245 | 0.87 | MAPK9 (0.54) | MAPK9MAPK10KDRCYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL27683877 | 0.85 | MAPK9 (0.53) | MAPK9MAPK10KDRCYP1A2CYP3A4 | |
| SCHEMBL27729355 | 0.85 | MAPKAPK2 (0.55) | MAPKAPK2MAPK9MAPK10KDRPTGS2 | |
| SCHEMBL26562756 | 0.84 | KDR (0.55) | MAPK9MAPK10LMNAKDRKDM4E | |
| SCHEMBL13772768 | 0.83 | MAPK9 (0.51) | MAPK9MAPK10KDRP2RX4 | |
| SCHEMBL20918400 | 0.83 | MAPK9 (0.51) | MAPK9MAPK10LMNAKDRKDM4E | |
| SCHEMBL17743635 | 0.83 | MAPK9 (0.51) | MAPK9MAPK10HSD17B10KDRCYP3A4 | |
| SCHEMBL10035798 | 0.83 | MAPK9 (0.51) | MAPK9MAPK10LMNAKDRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115286629-B | Method for preparing medicine intermediate 3-anilioimidazole [1,2-a ] pyridine derivative through catalysis | 安徽工业大学 | 2023-06-23 | — | — | CN | disclosed |
| CN-115286629-A | Method for preparing medical intermediate 3-phenylamino imidazole [1,2-a ] pyridine derivative through catalysis | 安徽工业大学 | 2022-11-04 | — | — | CN | disclosed |
| CN-109776529-A | A kind of synthetic method and application of 1,2- diones imidazole heterocyclic compounds | 国家烟草质量监督检验中心 | 2019-05-21 | — | — | CN | disclosed |