Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 11/20 | 0.61 |
| ▸ | DPP8 | Q6V1X1 | 5/20 | 0.61 |
| ▸ | DPP4 | P27487 | 10/20 | 0.60 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.54 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.53 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | KLK7 | P49862 | 2/20 | 0.49 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.49 |
| ▸ | F13A1 | P00488 | 1/20 | 0.47 |
| ▸ | TGM2 | P21980 | 1/20 | 0.47 |
| ▸ | TGM1 | P22735 | 1/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 1/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28302016 | 1.00 | DPP7 (0.61) | DPP7DPP8DPP4DPP9KCNH2 | |
| SCHEMBL28399421 | 0.88 | DPP7 (0.57) | DPP7DPP8DPP4DPP9KCNH2 | |
| SCHEMBL28269379 | 0.87 | TDP1 (0.47) | DPP7DPP8DPP9MAPTCTSK | |
| SCHEMBL28269377 | 0.87 | TDP1 (0.47) | DPP7DPP8DPP9MAPTCTSK | |
| SCHEMBL28619779 | 0.86 | EPHX2 (0.49) | DPP7DPP8DPP4DPP9 | |
| SCHEMBL28629697 | 0.85 | EPHX1 (0.48) | DPP7DPP8DPP4DPP9MAPT | |
| SCHEMBL20873003 | 0.84 | DPP8 (0.58) | DPP7DPP8DPP4DPP9ITGB3 | |
| SCHEMBL19708141 | 0.83 | DPP8 (0.57) | DPP7DPP8DPP4DPP9ITGB3 | |
| SCHEMBL19708142 | 0.83 | DPP8 (0.57) | DPP7DPP8DPP4DPP9ITGB3 | |
| SCHEMBL28618898 | 0.83 | TDP1 (0.46) | DPP7DPP8DPP4DPP9ITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109879934-A | A kind of salt and preparation method thereof of phenylpropionyl amine derivant | 江苏恒瑞医药股份有限公司 | 2019-06-14 | — | — | CN | disclosed |