Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | CRHBP | P24387 | 1/20 | 0.45 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.45 |
| ▸ | MGAM | O43451 | 1/20 | 0.45 |
| ▸ | SI | P14410 | 1/20 | 0.45 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | PPID | Q08752 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 1,2-Dimethoxybenzene SCHEMBL28113186 | 0.85 | ALDH1A1 (0.50) | CA4HPGDNPC1RAB9AGAA | |
| Acetoacetic Acid SCHEMBL11232644 | 0.84 | LMNA (0.47) | HPGDNPC1RAB9AGAAKMT2A | |
| Anisole SCHEMBL9445390 | 0.84 | CA4 (0.52) | CA4HPGDNPC1RAB9AGAA | |
| Toluene SCHEMBL8882403 | 0.84 | GAA (0.50) | NPC1RAB9AGAAMGAMSI | |
| Phenol SCHEMBL27983651 | 0.83 | GAA (0.49) | HPGDGAAMGAMSIMGAM2 | |
| SCHEMBL28365014 | 0.83 | GAA (0.48) | RAB9AGAAMGAMSIMGAM2 | |
| Anisole SCHEMBL2277975 | 0.82 | ALDH1A1 (0.54) | CA4CYP19A1HPGDNPC1RAB9A | |
| Benzene SCHEMBL28270557 | 0.82 | GAA (0.61) | GAAMGAMSIMGAM2KMT2A | |
| SCHEMBL8359021 | 0.81 | KMT2A (0.50) | HPGDKMT2ASMN1; SMN2GLAALDH1A1 | |
| Benzoic Acid SCHEMBL11314023 | 0.81 | DAO (0.48) | CYP19A1NPC1RAB9AGAAMGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109942523-A | A kind of benzofuran and benzofuran coumarin derivative and its preparation method and application | 华东师范大学 | 2019-06-28 | — | — | CN | disclosed |