Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ERN1 | O75460 | 6/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | PRKDC | P78527 | 1/20 | 0.33 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.32 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | GLS | O94925 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.31 |
| ▸ | TYR | P14679 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27447584 | 0.77 | ERN1 (0.41) | ALDH1A1KDM4ETSHRTDP1LMNA | |
| SCHEMBL28302358 | 0.76 | — | — | |
| SCHEMBL10835009 | 0.72 | PDGFRB (0.36) | ALDH1A1KDM4ETSHRLMNAMAPT | |
| SCHEMBL14192010 | 0.72 | PDGFRB (0.40) | ALDH1A1KDM4ETSHRTDP1LMNA | |
| SCHEMBL31092646 | 0.72 | TRPC6 (0.32) | ALDH1A1KDM4ETSHRHPGDPDGFRB | |
| SCHEMBL22042496 | 0.72 | TRPC6 (0.32) | ALDH1A1KDM4ETSHRHPGDPDGFRB | |
| SCHEMBL24457883 | 0.72 | ALDH1A1 (0.33) | ALDH1A1KDM4ETSHRHPGDPDGFRB | |
| SCHEMBL3539819 | 0.72 | ERN1 (0.40) | ALDH1A1KDM4ETSHRTDP1LMNA | |
| SCHEMBL16465631 | 0.72 | PRKDC (0.44) | ALDH1A1KDM4ETSHRTDP1LMNA | |
| SCHEMBL72221 | 0.71 | HTR2A (0.33) | PDGFRBPDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110036009-A | Substituted pyrrolidines and their use in the treatment of cystic fibrosis | 艾伯维公司 | 2019-07-19 | — | — | CN | disclosed |