Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | HBB | P68871 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.38 |
| ▸ | CES2 | O00748 | 2/20 | 0.35 |
| ▸ | CES1 | P23141 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL283030 | 1.00 | ALDH1A1 (0.52) | ALDH1A1MEN1LMNABLMHBB | |
| Bicarbonate SCHEMBL6906262 | 0.86 | ALDH1A1 (0.55) | ALDH1A1MEN1LMNABLMHBB | |
| Methyl Alcohol SCHEMBL11236519 | 0.86 | — | — | |
| SCHEMBL195349 | 0.86 | — | — | |
| Acetic Acid SCHEMBL10738465 | 0.84 | ALDH1A1 (0.52) | ALDH1A1MEN1LMNABLMHBB | |
| Bicarbonate SCHEMBL28197124 | 0.84 | ALDH1A1 (0.52) | ALDH1A1MEN1LMNABLMHBB | |
| Alcohol SCHEMBL11230369 | 0.83 | — | — | |
| Fluoride SCHEMBL27456165 | 0.83 | — | — | |
| Bromide SCHEMBL28182936 | 0.83 | — | — | |
| Heptane SCHEMBL6398285 | 0.76 | ALDH1A1 (0.80) | ALDH1A1TDP1TSHRCES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1199339-B1 | Water-reducible coating composition for providing corrosion protection | METAL COATINGS INT INC (US) | 2004-12-29 | — | — | EP | claimed |
| EP-1199339-A1 | Water-reducible coating composition for providing corrosion protection | Metal Coatings International Inc. (US) | 2002-04-24 | — | — | EP | claimed |
| US-6270884-B1 | Water-reducible coating composition for providing corrosion protection | METAL COATINGS INTERNATIONAL INC. | 2001-08-07 | — | — | US | claimed |
| US-20240101763-A1 | COMPOSITION COMPRISING ORGANIC FUNCTIONAL ALKOXYSILANES AND COATING COMPOSITIONS COMPRISING THE SAME | MOMENTIVE PERFORMANCE MATERIALS INC. | 2024-03-28 | — | — | US | disclosed |
| EP-4288497-A1 | COMPOSITION COMPRISING ORGANIC FUNCTIONAL ALKOXYSILANES AND COATING COMPOSITIONS COMPRISING THE SAME | Momentive Performance Materials Inc. (US) | 2023-12-13 | — | — | EP | disclosed |
| US-10676594-B2 | Reactive compositions containing mercapto-functional silicon compound | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2020-06-09 | — | — | US | disclosed |
| EP-3283577-B1 | REACTIVE COMPOSITIONS CONTAINING MERCAPTO-FUNCTIONAL SILICON COMPOUND | MOMENTIVE PERFORMANCE MAT INC (US) | 2019-07-17 | — | — | EP | disclosed |
| EP-1994080-B1 | LOW VOC EPOXY SILANE OLIGOMER AND COMPOSITIONS CONTAINING SAME | MOMENTIVE PERFORMANCE MAT INC (US) | 2019-01-16 | — | — | EP | disclosed |
| US-20190010309-A1 | REACTIVE COMPOSITIONS CONTAINING MERCAPTO-FUNCTIONAL SILICON COMPOUND | MOMENTIVE PERFORMANCE MATERIALS INC. | 2019-01-10 | — | — | US | disclosed |
| US-10106671-B2 | Reactive compositions containing mercapto-functional silicon compound | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2018-10-23 | — | — | US | disclosed |
| EP-3283577-A1 | REACTIVE COMPOSITIONS CONTAINING MERCAPTO-FUNCTIONAL SILICON COMPOUND | Momentive Performance Materials Inc. (US) | 2018-02-21 | — | — | EP | disclosed |
| WO-2007111769-A2 | LOW VOC EPOXY SILANE OLIGOMER AND COMPOSITIONS CONTAINING SAME | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2007-10-04 | — | — | WO | disclosed |
| US-20070179268-A1 | Low VOC epoxy silane oligomer and compositions containing same | MOMENTIVE PERFORMANCE MATERIALS INC. | 2007-08-02 | — | — | US | disclosed |
| WO-2007067203-A1 | EPOXY SILANE OLIGOMER AND COATING COMPOSITION CONTAINING SAME | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2007-06-14 | — | — | WO | disclosed |
| WO-2006110331-A1 | EPOXY SILANE OLIGOMER AND COATING COMPOSITION CONTAINING SAME | GENERAL ELECTRIC COMPANY (US) | 2006-10-19 | — | — | WO | disclosed |
| US-20060225613-A1 | Epoxy silane oligomer and coating composition containing same | MOMENTIVE PERFORMANCE MATERIALS INC. | 2006-10-12 | — | — | US | disclosed |
| US-20060225612-A1 | Epoxy silane oligomer and coating composition containing same | MOMENTIVE PERFORMANCE MATERIALS INC. | 2006-10-12 | — | — | US | disclosed |
| EP-1199339-B1 | Water-reducible coating composition for providing corrosion protection | METAL COATINGS INT INC (US) | 2004-12-29 | — | — | EP | disclosed |
| EP-1199339-A1 | Water-reducible coating composition for providing corrosion protection | Metal Coatings International Inc. (US) | 2002-04-24 | — | — | EP | disclosed |
| US-6270884-B1 | Water-reducible coating composition for providing corrosion protection | METAL COATINGS INTERNATIONAL INC. | 2001-08-07 | — | — | US | disclosed |